CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP1703
Family Name 2-amino-3-methylpentanoate NP 2-((3-(4-fluorophenoxy)-4-oxo-4h-chromen-7-yl)oxy)-2-oxoethanaminium 2,2,2-trifluoroacetate Family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00562040 Functional Category Natural Product
Superfamily Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibitor CHEMBL1414703 Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
DNA Binder Methoxsalen Family 10 1638
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Integrase Inhibitor L-708,906 Family 1 8
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A Inhibitor 3-aminoacetamido... 1 152
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Putative NP ZINC08790414 Family 23 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP Molport-006-318-109 Family 13 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
Putative NP ZINC04085259 Family 3 0
4-(7-((2-amino-3-phenylpropanoyl)oxy)-5-hydroxy-4-oxo-4H-chrom... 3 0
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
NP 5-hydroxy-4-oxo-2-phenyl-4h-chromen-7-yl 2-((tert-butoxycar... 19 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP 7-(2-((4as,8as)-4a-hydroxyoctahydroisoquinolin-2(1h)-yl)-2-... 3 0
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
bromobenzoate NP ZINC11865066 Family 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00562047 ZINC20111188 Natural Product 4-oxo-3-phenoxy-4H-chromen-7-yl 2-amino-3-methylpentanoate hydrochloride
CFAMM00562040 ZINC20111184 Natural Product AC1LWMM8
CFAMM00562053 ZINC19703095 Natural Product (S)-3-(4-fluorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl 2-amino-3-methylbutanoate hydrochloride
CFAMM00562052 ZINC02124009 Natural Product AC1LWLP8
CFAMM00562045 ZINC20111190 Natural Product AC1LWMM2
CFAMM00562051 ZINC02124006 Natural Product (2R)-4-oxo-3-phenoxy-4H-chromen-7-yl 3-methyl-2-((pivaloyloxy)amino)pentanoate
CFAMM00562044 ZINC20111201 Natural Product (2R)-3-(3-fluorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl 2-amino-3-methylpentanoate hydrochloride
CFAMM00562050 ZINC20113377 Natural Product 2-((3-(4-fluorophenoxy)-4-oxo-4H-chromen-7-yl)oxy)-2-oxoethanaminium 2,2,2-trifluoroacetate
CFAMM00562043 ZINC20111202 Natural Product AC1LUHNG
CFAMM00562049 ZINC32109468 Natural Product [(5R)-5-amino-6-[3-(4-methoxyphenyl)-4-oxochromen-7-yl]oxy-6-oxohexyl]azanium
CFAMM00562042 ZINC19703007 Natural Product (R)-3-(4-fluorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl 2-amino-4-methylpentanoate hydrochloride
CFAMM00562048 ZINC19703438 Natural Product (R)-1-((3-(4-fluorophenoxy)-4-oxo-4H-chromen-7-yl)oxy)-1-oxopropan-2-aminium bromide
CFAMM00562041 ZINC20111186 Natural Product AC1LWMME

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38795 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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