CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2036
Family Name NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)methyl)-6,7-dimethyl-2h-chromen-2-one Family
No. of Seeds 14 No. of Other Members 0
Family Centroid CFAMM00563984 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Integrase Inhibitor L-708,906 Family 1 8
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Protein kinase C gamma type and Protein kinase C alpha type In... 2 1
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
2-amino-3-methylpentanoate NP 2-((3-(4-fluorophenoxy)-4-oxo-4h... 13 2
NP 2,2,11,12-tetramethyl-3,4,8,9-tetrahydro-2h-cyclopenta[c]fu... 3 1
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
Putative NP ZINC05155929 Family 6 0
Putative NP ZINC13787156 Family 4 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
bromobenzoate NP ZINC11865066 Family 6 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00563988 ZINC01777094 Natural Product 3-(4-chlorophenyl)-4-oxo-4H-chromen-7-yl 3-methoxybenzoate
CFAMM00563980 ZINC02152097 Natural Product 4-(((3-(4-chlorophenyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)-5,7-dimethyl-2H-chromen-2-one
CFAMM00563987 ZINC01959516 Natural Product ST50071377
CFAMM00563979 ZINC02425692 Natural Product ST50071245
CFAMM00563986 ZINC01959510 Natural Product ST50071405
CFAMM00563977 ZINC01447985 Natural Product ST50071374
CFAMM00563985 ZINC01770969 Natural Product [3-(4-chlorophenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] 4-methylbenzoate
CFAMM00563976 ZINC02096281 Natural Product 4-(((3-(4-chlorophenyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)-6,7-dimethyl-2H-chromen-2-one
CFAMM00563984 ZINC02091526 Natural Product 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)methyl)-7-methoxy-2H-chromen-2-one
CFAMM00563975 ZINC02429037 Natural Product ST50071388
CFAMM00563990 ZINC02149843 Natural Product 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)methyl)-6,7-dimethyl-2H-chromen-2-one
CFAMM00563983 ZINC02095314 Natural Product 4-(((3-(4-chlorophenyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)-7-methoxy-2H-chromen-2-one
CFAMM00563989 ZINC02416877 Natural Product ST50071371
CFAMM00563982 ZINC02095629 Natural Product 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)methyl)-5,7-dimethyl-2H-chromen-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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