CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2053
Family Name NP 4-(chloromethyl)-6-methoxy-2h-chromen-2-one Family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00564070 Functional Category Natural Product
Superfamily dimethylchromen-2-one NP 4-(chloromethyl)-6,7-dimethyl-2h-chromen-2-one Superfamily
Class Class 432

Cousin Family NamesSeedsMembers
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor (4-met... 1 1
NS5B protein inhibitor (Z)-4-[2-(3-cyanopropoxy)phenyl]-4-hydr... 2 0
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 2 4
2-methyl-2H-chromene-3-carbaldehyde NP 2-methyl-2h-chromene-3-... 2 1
dimethylchromen-2-one NP 4-(chloromethyl)-6,7-dimethyl-2h-chro... 5 2


External ID

Functional Category

Molecule Name

CFAMM00564074 ZINC00538785 Natural Product 4-(chloromethyl)-6-hydroxy-7-phenylchromen-2-one
CFAMM00564071 ZINC00541577 Natural Product 4-(chloromethyl)-6-hydroxychromen-2-one
CFAMM00564070 ZINC00538058 Natural Product 4-(chloromethyl)-6-hydroxy-7-methylchromen-2-one
CFAMM00564069 ZINC20349008 Natural Product 4-(chloromethyl)-6-methoxy-2H-chromen-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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