CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2088
Family Name Putative NP ZINC38570085 Family
No. of Seeds 14 No. of Other Members 0
Family Centroid CFAMM00564301 Functional Category Natural Product
Superfamily NP 3-((1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyclohexyl)oxy)propanenitrile and NP 2-methyl-5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-2-yl Acetate Superfamily
Class Class 484

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3R family 1 1
Neuronal acetylcholine receptor subunit alpha-6 ligand AGN-PC-... 2 0
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 2 1
Acetylcholine-binding protein and Neuronal acetylcholine recep... 1 5
NP 3-((1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyc... 12 0
NP 2-methyl-5-(2-(pyridin-3-yl)piperidin-1-yl)pent-3-yn-2-yl A... 8 1
Putative NP ZINC19701930 Family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00564301 ZINC38570253 Natural Product ZINC08792010
CFAMM00564294 ZINC38193787 Natural Product (3S)-2,2,3-trimethyl-6-[(2S)-2-pyridin-3-ylpiperidin-1-ium-1-yl]hex-4-yn-3-ol
CFAMM00564300 ZINC55243736 Natural Product AC1OJZ9H
CFAMM00564293 ZINC38193788 Natural Product (3R)-2,2,3-trimethyl-6-[(2S)-2-pyridin-3-ylpiperidin-1-ium-1-yl]hex-4-yn-3-ol
CFAMM00564299 ZINC38570085 Natural Product ZINC04000271
CFAMM00564292 ZINC55243742 Natural Product 1-(3-(2-(pyridin-3-yl)piperidin-1-yl)prop-1-yn-1-yl)cyclopentanol
CFAMM00564298 ZINC38570087 Natural Product ZINC04000272
CFAMM00564291 ZINC55243460 Natural Product (4S)-4-hydroxy-4-methyl-7-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hept-5-yn-2-one
CFAMM00564297 ZINC38570258 Natural Product ZINC08790660
CFAMM00564303 ZINC38570261 Natural Product ZINC08790662
CFAMM00564290 ZINC55243467 Natural Product (4R)-4-hydroxy-4-methyl-7-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hept-5-yn-2-one
CFAMM00564296 ZINC55231618 Natural Product (3S)-2,3-dimethyl-6-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hex-1-en-4-yn-3-ol
CFAMM00564302 ZINC38570264 Natural Product ZINC08790664
CFAMM00564295 ZINC55231620 Natural Product (3R)-2,3-dimethyl-6-[(2R)-2-pyridin-3-ylpiperidin-1-yl]hex-1-en-4-yn-3-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27052 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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