CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2142
Family Name 2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate NP ZINC00132596 Family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00564634 Functional Category Natural Product
Superfamily Muscleblind-like protein 1 and Tyrosyl-DNA phosphodiesterase 1 Binder Superfamily 3
Class Class 366

Cousin Family NamesSeedsMembers
Lipoprotein lipase Inhibitor Gemfibrozil Family 1 28
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Ipriflavone family 62 2480
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Histone deacetylase 2 and Histone deacetylase 8 inhibitor AC1L... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 78
Platelet-activating factor receptor ligand (2S,3R,3aS)-2-(3,4-... 2 7
Free fatty acid receptor 1 ligand 3-[4-[2-[3-(trifluoromethoxy... 1 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
NS5B protein inhibitor SureCN3988565 family 2 4
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Benzoxepines Metabolite 4,5-Dihydro-1-benzoxepin-3(2H)-one Family 1 2
Putative NP ZINC31165975 Family 4 0
Putative NP ZINC31158464 Family 3 5
Putative NP ZINC04043753 Family 8 6
benzofuran-2-one NP 5-hydroxybenzofuran-2(3h)-one Family 1 0
3-pentyl-5-(phenoxymethyl)oxolan-2-one NP ZINC02116245 Family 4 0
2-[(3,4-dimethoxyphenyl)methyl]propanedioate NP 4aji Family 1 0
5-(4-methoxyphenyl)-2,2-dimethyloxolan-3-one NP 5-(4-methoxyph... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00564633 ZINC00132596 Natural Product (2S,3R)-2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate
CFAMM00564632 ZINC04023342 Natural Product AC1OFF3G
CFAMM00564631 ZINC00184494 Natural Product (2S)-2-[(2-methoxyphenyl)methyl]butanedioate
CFAMM00564634 ZINC00132594 Natural Product (2R,3R)-2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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