CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2279
Family Name pyrrolidine-1,2-dicarboxylate NP ZINC04028685 Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00565514 Functional Category Natural Product
Superfamily Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand 1-[2-[methyl(2-phenylethyl)amino]-2-oxoethyl]-4-phenylmethoxy-3a,4-dihydroindole-3-carboxylic acid Superfamily
Class Class 3304

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Prolyl endopeptidase and Chymotrypsin-like elastase family mem... 3 9
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 2 2
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 4 27
Neutrophil elastase inhibitor benzyl N-[(2S)-3-methyl-1-[(2S)-... 2 0
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 4 7
Cathepsin S inhibitor (2R)-N-[(1R)-2-[(4-chlorophenyl)methoxy]... 2 0
Solute carrier family 12 member 5 inhibitor AGN-PC-07ZCLM family 1 12
Putative NP ZINC16043224 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00565514 ZINC04028685 Natural Product 2-O-[[(1S,9aS)-5-methyl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-5-ium-1-yl]methyl] 1-O-benzyl (2S)-pyrrolidine-1,2-dicarboxylate
CFAMM00565513 ZINC04028686 Natural Product 2-O-[[(1S,9aS)-5-methyl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-5-ium-1-yl]methyl] 1-O-benzyl (2R)-pyrrolidine-1,2-dicarboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543