CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2483
Family Name carboxylate NP ZINC04026424 Family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00566675 Functional Category Natural Product
Superfamily Indanes Metabolite (R)-Pterosin B Superfamily
Class Class 5465

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
RAC-alpha serine/threonine-protein kinase inhibitor CHEMBL4754... 2 17
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Integrase inhibitor AGN-PC-00QHSA family 1 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 4
Tyrosine-protein phosphatase non-receptor type 1 ligand AGN-PC... 1 1
Indanes Metabolite (R)-Pterosin B Family 5 8
(1S)-1-hydroxy-1,4-dimethyl-2,3-dihydrocyclopenta[b]anthracene... 1 1
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
3-(4-hydroxy-6-methyl-2-oxopyran-3-yl)-3H-2-benzofuran-1-one N... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00566670 ZINC04026424 Natural Product 2-[(E)-3-phenylprop-2-enoyl]benzoate
CFAMM00566675 ZINC00193186 Natural Product 7-methyl-9-oxofluorene-1-carboxylate
CFAMM00566677 ZINC03896824 Natural Product Anthraquinone-2-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

84154 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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