Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
Cousin Family Names Seeds Members Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827 DNA Binder Methoxsalen Family 10 1638 D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364 Hidrosmin family 14 61 Ipriflavone family 62 2480 Rotenone family 16 107 Agrimophol family 10 22 Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79 Steryl-sulfatase Inhibitor Stx 64 Family 7 160 Endothelin-1 receptor Ligand PD156707 Family 41 211 cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81 Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127 Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57 Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11 Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 4 102 MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17 Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86 Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9 Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64 Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40 Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-deh... 1 7 Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26 Putative NP ZINC02398203 Family 1 0 NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0 NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0 1,3-dimethylcyclohepta[c]furan-8-one NP 6-(4-hydroxy-3-iodo-5-... 13 1 2H,2'H-[3,4'-bichromene]-2,2'-dione NP 7'-((3-bromobenzyl)oxy)... 3 0 NP Ethyl 3-(4-bromophenyl)-7-((methylsulfonyl)oxy)-4-oxo-4h-ch... 9 1 NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4 NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0 NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0 NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0 NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0 benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0 4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1 NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1 NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3 Putative NP ZINC09486076 Family 56 0 bromobenzoate NP ZINC09346025 Family 20 0 Putative NP ZINC09305195 Family 19 0 1-benzofuran-3-one NP ZINC02367988 Family 9 0 1-benzofuran-3-one NP ZINC02423517 Family 24 0 benzenesulfonate NP ZINC09051160 Family 47 2 Putative NP ZINC02424323 Family 24 0 NP Af-399/42316321 Family 7 0 2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0 1-benzofuran-3-one NP ZINC02424004 Family 22 0 Putative NP ZINC02424496 Family 5 0 Putative NP ZINC09051797 Family 10 0 Putative NP ZINC09306352 Family 7 0 Putative NP ZINC09575270 Family 7 0 Putative NP ZINC01135787 Family 3 0 NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0 Putative NP ZINC09517236 Family 5 0
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Dr.
Chen Yuzong
Deputy
Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
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