CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2519
Family Name NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benzofuran-3(2h)-one Family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00566824 Functional Category Natural Product
Superfamily 4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2-oxoethoxy)-4-methyl-2-oxo-2h-chromen-3-yl)propanoate and bromobenzoate NP ZINC09346025 Superfamily
Class Class 4333

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Endothelin-1 receptor Ligand PD156707 Family 41 211
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 4 102
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-deh... 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Putative NP ZINC02398203 Family 1 0
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
1,3-dimethylcyclohepta[c]furan-8-one NP 6-(4-hydroxy-3-iodo-5-... 13 1
2H,2'H-[3,4'-bichromene]-2,2'-dione NP 7'-((3-bromobenzyl)oxy)... 3 0
NP Ethyl 3-(4-bromophenyl)-7-((methylsulfonyl)oxy)-4-oxo-4h-ch... 9 1
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3
Putative NP ZINC09486076 Family 56 0
bromobenzoate NP ZINC09346025 Family 20 0
Putative NP ZINC09305195 Family 19 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
NP Af-399/42316321 Family 7 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
Putative NP ZINC02424496 Family 5 0
Putative NP ZINC09051797 Family 10 0
Putative NP ZINC09306352 Family 7 0
Putative NP ZINC09575270 Family 7 0
Putative NP ZINC01135787 Family 3 0
NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0
Putative NP ZINC09517236 Family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00566823 ZINC02222017 Natural Product ST50472192
CFAMM00566814 ZINC02413161 Natural Product 7-[(4-bromophenyl)methoxy]-3-(2-ethoxyphenoxy)chromen-4-one
CFAMM00566829 ZINC09304790 Natural Product AC1O6LTH
CFAMM00566822 ZINC01321188 Natural Product ethyl 7-((2-bromobenzoyl)oxy)-3-(3,4-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxylate
CFAMM00566828 ZINC02433802 Natural Product ST50472177
CFAMM00566821 ZINC02425475 Natural Product 7-[(4-bromophenyl)methoxy]-3-(2-methoxyphenoxy)chromen-4-one
CFAMM00566827 ZINC02422798 Natural Product AC1M09AH
CFAMM00566820 ZINC09281721 Natural Product AC1O6O7K
CFAMM00566826 ZINC01463956 Natural Product 3-(3,4-dimethoxyphenyl)-2-methyl-4-oxo-4H-chromen-7-yl 4-bromobenzoate
CFAMM00566825 ZINC02377212 Natural Product AC1LZYVB
CFAMM00566817 ZINC02103781 Natural Product (Z)-6-((4-bromobenzyl)oxy)-2-(3,4,5-trimethoxybenzylidene)benzofuran-3(2H)-one
CFAMM00566824 ZINC00938713 Natural Product (Z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benzofuran-3(2H)-one
CFAMM00566815 ZINC09348579 Natural Product AC1NM4OQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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