CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2534
Family Name (8-methyl-6-oxo-1,2,3a,4,5,6-hexahydro-3H-3,10b-diazaacephenanthrylen-3-yl)acetonitrile NP (s)-2-(8-methyl-6-oxo-4,5-dihydro-1h-3,10b-diazaacephenanthrylen-3(2h,3ah,6h)-yl)acetonitrile Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00566897 Functional Category Natural Product
Superfamily Acetylcholinesterase and Niemann-Pick C1 protein Binder Superfamily
Class Class 2521

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
K-604 family 4 71
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 1
Histamine H3 receptor ligand SureCN3058680 family 4 0
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1


External ID

Functional Category

Molecule Name

CFAMM00566897 ZINC19300805 Natural Product (S)-2-(8-methyl-6-oxo-4,5-dihydro-1H-3,10b-diazaacephenanthrylen-3(2H,3aH,6H)-yl)acetonitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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