CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2548
Family Name 1,4,4a,5,6,8a-hexahydropyrimido[4,5-d]pyrimidine-2,7-dione NP ZINC04026519 Family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00566962 Functional Category Natural Product
Superfamily Beta-lactamase and Cholinesterase Binder Superfamily 6
Class Class 3513

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Zucapsacin family 7 177
3-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)amino... 3 0
1,3-diazaadamantan-6-one NP ZINC19323291 Family 15 0
Putative NP ZINC19322380 Family 2 2
1,3-diazaadamantan-6-ol NP ZINC19320140 Family 16 0
Putative NP ZINC04287792 Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00566965 ZINC04029454 Natural Product (4S,4aS,5R,8aR)-4-(4-hydroxy-3-methoxyphenyl)-1,3,5,6,8-pentamethyl-4,4a,5,8a-tetrahydropyrimido[4,5-d]pyrimidine-2,7-dione
CFAMM00566971 ZINC04026520 Natural Product (4aS,8aS)-5-(4-hydroxy-3-methoxyphenyl)-1,4,6-trimethylhexahydropyrimido[4,5-d]pyrimidine-2,7(1H,3H)-dione
CFAMM00566964 ZINC04029453 Natural Product (4aS,8aR)-4-(4-hydroxy-3-methoxyphenyl)-1,3,5,6,8-pentamethylhexahydropyrimido[4,5-d]pyrimidine-2,7(1H,3H)-dione
CFAMM00566970 ZINC01025817 Natural Product AC1LOG2S
CFAMM00566963 ZINC04026522 Natural Product (4S,4aS,5S,8aS)-4-(4-hydroxy-3-methoxyphenyl)-3,5,8-trimethyl-1,4,4a,5,6,8a-hexahydropyrimido[4,5-d]pyrimidine-2,7-dione
CFAMM00566969 ZINC04029228 Natural Product AC1OCVII
CFAMM00566962 ZINC04026519 Natural Product (4R,4aS,5R,8aS)-4-(4-hydroxy-3-methoxyphenyl)-3,5,8-trimethyl-1,4,4a,5,6,8a-hexahydropyrimido[4,5-d]pyrimidine-2,7-dione
CFAMM00566968 ZINC04029227 Natural Product AC1OCVIL
CFAMM00566961 ZINC04026521 Natural Product (4S,4aS,5R,8aS)-4-(4-hydroxy-3-methoxyphenyl)-3,5,8-trimethyl-1,4,4a,5,6,8a-hexahydropyrimido[4,5-d]pyrimidine-2,7-dione
CFAMM00566967 ZINC04029225 Natural Product AC1OCVIR
CFAMM00566960 ZINC04029455 Natural Product (4S,4aS,5S,8aR)-4-(4-hydroxy-3-methoxyphenyl)-1,3,5,6,8-pentamethyl-4,4a,5,8a-tetrahydropyrimido[4,5-d]pyrimidine-2,7-dione
CFAMM00566966 ZINC04029226 Natural Product (4aS,8aS)-1,4,6-trimethyl-5-(3,4,5-trimethoxyphenyl)hexahydropyrimido[4,5-d]pyrimidine-2,7(1H,3H)-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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