CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2573
Family Name dimethylchromen-2-one NP 4-(chloromethyl)-6,7-dimethyl-2h-chromen-2-one Family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00567095 Functional Category Natural Product
Superfamily dimethylchromen-2-one NP 4-(chloromethyl)-6,7-dimethyl-2h-chromen-2-one Superfamily
Class Class 432

Cousin Family NamesSeedsMembers
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Tretinoin Tocoferil family 1 13
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Aromatase Inhibitor NSC-122427 Family 1 0
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Androgen receptor Ligand Palodesangren E Family 12 43
NP Agn-pc-05grlk Family 2 1
NP 4-(chloromethyl)-6-methoxy-2h-chromen-2-one Family 4 2
NP 6-chloro-4-(chloromethyl)-5,7-dimethylchromen-2-one Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00567094 ZINC00534664 Natural Product F3139-1618
CFAMM00567098 ZINC00541089 Natural Product 4-(chloromethyl)-5,7,8-trimethylchromen-2-one
CFAMM00567097 ZINC00537607 Natural Product 4-(chloromethyl)-7,8-dihydrocyclopenta[g]chromen-2(6H)-one
CFAMM00567096 ZINC00489403 Natural Product 4-(chloromethyl)-6,8-dimethyl-2H-chromen-2-one
CFAMM00567095 ZINC00489177 Natural Product 4-(chloromethyl)-6,7-dimethyl-2H-chromen-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



53955 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543