CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2604
Family Name 3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-ol Family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00567207 Functional Category Natural Product
Superfamily Voltage-gated sodium channel Ligand Oxcarbazepine Superfamily
Class Class 311

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Voltage-gated sodium channel Ligand Oxcarbazepine Family 1 4
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Serum albumin Inhibitor Ebselen Family 3 62
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Glutamate receptor ionotropic, NMDA 1 Ligand Dcka, 5,7-dichlor... 2 7
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 4-methyl-5,6... 3 12
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-... 1 4
Transient receptor potential cation channel subfamily V member... 6 33
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 1 9
Androgen receptor Ligand 6-n-propyl -4-trifluoromethylquinolin... 29 13
Liver carboxylesterase 1 Inhibitor 7-(trifluoromethyl)-1h-indo... 1 1
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Transient receptor potential cation channel subfamily V member... 1 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Benz... 3 12
Poly [ADP-ribose] polymerase 1 Inhibitor 5-aminoisoquinolin-1(... 2 8
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Myeloperoxidase Inhibitor 4-aminobenzoic Acid Hydrazide Family 1 3
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 8 1
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 2 4
Acetylcholinesterase inhibitor tmtfa family 1 2
Caspase-3 inhibitor Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1... 2 3
Cytochrome P450 2C19 and 3-hydroxyacyl-CoA dehydrogenase type-... 1 5
1H-quinolin-4-one NP 4-(6-bromo-4-hydroxy-2-methylquinolin-3-y... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00567209 ZINC08738279 Natural Product 3-allyl-6-amino-2-methylquinolin-4-ol
CFAMM00567208 ZINC08581335 Natural Product 3-ethyl-2,8-dimethylquinolin-4-ol
CFAMM00567207 ZINC08733395 Natural Product 6-amino-2-methylquinolin-4-ol
CFAMM00567206 ZINC08716707 Natural Product 6-amino-2-methyl-3-(3-oxobutyl)quinolin-4(1H)-one
CFAMM00567203 ZINC08740167 Natural Product 3-allyl-2,8-dimethylquinolin-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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