CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP2988
Family Name 2-(2,3,4,8,9,10-hexahydro-[1,4]dioxepino[2,3-g]isoquinolin-7-ylidene)ethanone NP (z)-1-cyclobutyl-2-(7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-5(6h)-ylidene)ethanone Family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00568815 Functional Category Natural Product
Superfamily Acetylcholinesterase Inhibitor Donepezil Superfamily
Class Class 333

Cousin Family NamesSeedsMembers
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Putative NP ZINC04287792 Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00568817 ZINC04090315 Natural Product (Z)-1-cyclobutyl-2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-ylidene)ethanone
CFAMM00568816 ZINC04090556 Natural Product (Z)-1-cyclopentyl-2-(3,4,9,10-tetrahydro-2H-[1,4]dioxepino[2,3-g]isoquinolin-7(8H)-ylidene)ethanone
CFAMM00568815 ZINC04090528 Natural Product (Z)-1-cyclobutyl-2-(3,4,9,10-tetrahydro-2H-[1,4]dioxepino[2,3-g]isoquinolin-7(8H)-ylidene)ethanone
CFAMM00568814 ZINC04090238 Natural Product (Z)-1-cyclobutyl-2-(7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-ylidene)ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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