CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3017
Family Name 6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione NP ZINC02096351 Family
No. of Seeds 16 No. of Other Members 0
Family Centroid CFAMM00568974 Functional Category Natural Product
Superfamily Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor Binder Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Histone deacetylase Inhibitor ST-5732 Family 8 6
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 18
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 6 4
KiSS-1 receptor ligand SureCN5132924 family 2 4
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 11 0
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 16 0
(S)-2-amino-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4... 1 0
2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(1... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00568966 ZINC02095912 Natural Product AC1LWK72
CFAMM00568972 ZINC02147985 Natural Product AC1LXDG6
CFAMM00568965 ZINC02096351 Natural Product AC1LWKW2
CFAMM00568971 ZINC02159371 Natural Product AC1LXT3V
CFAMM00568964 ZINC02094307 Natural Product AC1LWI0N
CFAMM00568970 ZINC02150651 Natural Product AC1LXJZ0
CFAMM00568963 ZINC02096353 Natural Product (12aS)-2-(3-hydroxypropyl)-6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568969 ZINC02147982 Natural Product (12aS)-2-(3-isopropoxypropyl)-6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568962 ZINC02094306 Natural Product (12aS)-6-(3-nitrophenyl)-2-((tetrahydrofuran-2-yl)methyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568975 ZINC02091646 Natural Product AC1LXAPI
CFAMM00568968 ZINC02094304 Natural Product AC1LWI0H
CFAMM00568961 ZINC08952490 Natural Product (12aS)-2-(2,2-dimethoxyethyl)-6-(4-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568974 ZINC02091645 Natural Product (12aS)-2-(3-butoxypropyl)-6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568967 ZINC02094309 Natural Product AC1LWI0Q
CFAMM00568960 ZINC02095914 Natural Product (12aS)-2-(5-hydroxypentyl)-6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione
CFAMM00568973 ZINC02150649 Natural Product tert-butyl ((12aS)-6-(3-nitrophenyl)-1,4-dioxo-3,4,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H,6H,7H)-yl)carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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