CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3171
Family Name NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl 2-chlorobenzoate Family
No. of Seeds 74 No. of Other Members 1
Family Centroid CFAMM00569628 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
Keratin Inhibitor Griseofulvin Family 1 11
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Integrase Inhibitor L-708,906 Family 1 8
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Peroxisome proliferator-activated receptor alpha and Peroxisom... 7 6
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 13
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 3-(4-chlorophenyl)-4,9-dimethyl-7h-furo[2,3-f]chromen-7-one... 18 0
NP Ethyl 3-(4-bromophenyl)-7-((methylsulfonyl)oxy)-4-oxo-4h-ch... 9 1
NP 6-chloro-7-(2-(4-chlorophenyl)-2-oxoethoxy)-4-phenyl-2h-chr... 2 3
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
2-amino-3-methylpentanoate NP 2-((3-(4-fluorophenoxy)-4-oxo-4h... 13 2
3-(4-chlorophenoxy)-2-methyl-4-oxo-4H-chromen-7-yl 2-(((benzyl... 2 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
8-methyl-4-(2-oxochromen-3-yl)chromen-2-one NP 7'-((2,6-dichlo... 3 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
Putative NP ZINC05155929 Family 6 0
Putative NP ZINC09486076 Family 56 0
Putative NP ZINC13787156 Family 4 0
Putative NP ZINC09305195 Family 19 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
Putative NP ZINC01135787 Family 3 0
NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0
Putative NP ZINC09517236 Family 5 0
bromobenzoate NP ZINC11865066 Family 6 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00569620 ZINC09418554 Natural Product AC1O3SBQ
CFAMM00569574 ZINC11869034 Natural Product AC1LY4GH
CFAMM00569587 ZINC05437263 Natural Product [(2Z)-2-[(2-chloro-6-fluorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] propanoate
CFAMM00569600 ZINC09158004 Natural Product AC1M00K2
CFAMM00569613 ZINC02417720 Natural Product AC1M02PK
CFAMM00569626 ZINC05196544 Natural Product [(2Z)-2-[(2-chloro-6-fluorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] acetate
CFAMM00569567 ZINC11868883 Natural Product AC1M09EK
CFAMM00569580 ZINC09215960 Natural Product AC1NYLNI
CFAMM00569606 ZINC02428066 Natural Product AC1M0FYI
CFAMM00569593 ZINC05255244 Natural Product AC1M0QIZ
CFAMM00569619 ZINC02134714 Natural Product AC1LX050
CFAMM00569632 ZINC13777302 Natural Product AC1M07SQ
CFAMM00569573 ZINC09281444 Natural Product AC1LZXM9
CFAMM00569586 ZINC02105137 Natural Product (Z)-methyl 4-((6-((2-chlorobenzyl)oxy)-3-oxobenzofuran-2(3H)-ylidene)methyl)benzoate
CFAMM00569599 ZINC02415848 Natural Product AC1M00DH
CFAMM00569612 ZINC09306628 Natural Product AC1O3SC5
CFAMM00569625 ZINC11868616 Natural Product AC1LZUJF
CFAMM00569566 ZINC02157999 Natural Product (Z)-2-(2,4-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl 2-chlorobenzoate
CFAMM00569579 ZINC09282080 Natural Product AC1M04AD
CFAMM00569638 ZINC02235167 Natural Product AC1LY5TT
CFAMM00569592 ZINC09281180 Natural Product AC1LZV3O
CFAMM00569605 ZINC11866181 Natural Product (Z)-2-((2H-chromen-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl 4-chlorobenzoate
CFAMM00569631 ZINC02436284 Natural Product AC1M0RDQ
CFAMM00569572 ZINC13779122 Natural Product AC1M0DWD
CFAMM00569618 ZINC02138089 Natural Product (Z)-2-((2H-chromen-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl 2-chlorobenzoate
CFAMM00569585 ZINC05254703 Natural Product [(2Z)-2-[(2,6-dichlorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] acetate
CFAMM00569598 ZINC09280922 Natural Product AC1LZSXL
CFAMM00569611 ZINC02231717 Natural Product AC1LY1DH
CFAMM00569624 ZINC13776995 Natural Product AC1LJ4O4
CFAMM00569565 ZINC13776782 Natural Product AC1LJ49U
CFAMM00569578 ZINC09184174 Natural Product AC1O3SBB
CFAMM00569637 ZINC13768823 Natural Product AC1LZX0H
CFAMM00569591 ZINC09185579 Natural Product AC1M0BJE
CFAMM00569604 ZINC02409563 Natural Product AC1LZS54
CFAMM00569617 ZINC09419153 Natural Product AC1O3SAQ
CFAMM00569571 ZINC09216492 Natural Product AC1LZO5O
CFAMM00569630 ZINC05390086 Natural Product AC1LXKP8
CFAMM00569584 ZINC13625448 Natural Product AC1O3S98
CFAMM00569597 ZINC13629763 Natural Product AC1O3THK
CFAMM00569610 ZINC09215600 Natural Product AC1O0TG0
CFAMM00569623 ZINC13778964 Natural Product AC1M0D2I
CFAMM00569564 ZINC02398385 Natural Product AC1M0E0A
CFAMM00569577 ZINC09345963 Natural Product AC1O3DA0
CFAMM00569590 ZINC09192213 Natural Product AC1LZIOS
CFAMM00569636 ZINC02099245 Natural Product (Z)-methyl 4-((6-((3-chlorobenzyl)oxy)-3-oxobenzofuran-2(3H)-ylidene)methyl)benzoate
CFAMM00569603 ZINC09159119 Natural Product AC1LYFFK
CFAMM00569616 ZINC09158174 Natural Product AC1NY086
CFAMM00569570 ZINC09341735 Natural Product AC1O3THN
CFAMM00569629 ZINC09209748 Natural Product AC1M0GAW
CFAMM00569583 ZINC11868867 Natural Product AC1NZ0T4
CFAMM00569596 ZINC13778067 Natural Product AC1M07FY
CFAMM00569609 ZINC02398197 Natural Product AC1M0DSK
CFAMM00569622 ZINC13787190 Natural Product AC1M0VBB
CFAMM00569635 ZINC05162686 Natural Product AC1LY5F3
CFAMM00569576 ZINC05577114 Natural Product [(2Z)-2-[(2-fluorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] 4-chlorobenzoate
CFAMM00569589 ZINC11869540 Natural Product AC1LZ7ZD
CFAMM00569602 ZINC00541359 Natural Product [(2Z)-2-[(3-chlorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] cyclopropanecarboxylate
CFAMM00569615 ZINC13629976 Natural Product AC1O3THQ
CFAMM00569569 ZINC09210206 Natural Product AC1M0OG3
CFAMM00569628 ZINC04514781 Natural Product AC1LUD3S
CFAMM00569582 ZINC05157980 Natural Product [(2Z)-2-[(2,6-dichlorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] cyclopropanecarboxylate
CFAMM00569595 ZINC09185469 Natural Product AC1M09B8
CFAMM00569608 ZINC05577633 Natural Product AC1M135N
CFAMM00569621 ZINC02134711 Natural Product (Z)-2-((2-methyl-2H-chromen-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl 4-chlorobenzoate
CFAMM00569634 ZINC13769140 Natural Product AC1M00GN
CFAMM00569575 ZINC11868896 Natural Product AC1M0I4H
CFAMM00569588 ZINC13769117 Natural Product AC1M003Y
CFAMM00569601 ZINC13769828 Natural Product AC1M06S4
CFAMM00569614 ZINC02128137 Natural Product (Z)-2-((2-methyl-2H-chromen-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl 2-chlorobenzoate
CFAMM00569581 ZINC02096983 Natural Product (Z)-2-(2,5-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl 2-chlorobenzoate
CFAMM00569627 ZINC09420180 Natural Product AC1O3SAT
CFAMM00569568 ZINC09346407 Natural Product AC1O6XI5
CFAMM00569594 ZINC02401311 Natural Product AC1M0GTC
CFAMM00569607 ZINC02128142 Natural Product AC1LWRLP

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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