CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3475
Family Name 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate Family
No. of Seeds 27 No. of Other Members 0
Family Centroid CFAMM00570672 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 13
Arachidonate 5-lipoxygenase inhibitor SureCN9740792 family 2 6
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 3-(4-chlorophenyl)-4,9-dimethyl-7h-furo[2,3-f]chromen-7-one... 18 0
NP 6-chloro-7-(2-(4-chlorophenyl)-2-oxoethoxy)-4-phenyl-2h-chr... 2 3
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
3-(4-chlorophenoxy)-2-methyl-4-oxo-4H-chromen-7-yl 2-(((benzyl... 2 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
Putative NP ZINC05155929 Family 6 0
Putative NP ZINC09486076 Family 56 0
Putative NP ZINC13787156 Family 4 0
Putative NP ZINC09305195 Family 19 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0
NP Agn-pc-00z9li Family 2 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00570663 ZINC13769816 Natural Product AC1M06PP
CFAMM00570676 ZINC13769110 Natural Product AC1M002M
CFAMM00570669 ZINC05164825 Natural Product AC1LZY30
CFAMM00570682 ZINC05156365 Natural Product (2Z)-6-[(3-chlorophenyl)methoxy]-2-[(5-methylfuran-2-yl)methylidene]-1-benzofuran-3-one
CFAMM00570662 ZINC05191347 Natural Product AC1LZPZW
CFAMM00570675 ZINC02198768 Natural Product AC1LXNDR
CFAMM00570681 ZINC13759667 Natural Product AC1LZS7U
CFAMM00570668 ZINC13768451 Natural Product AC1LZTKF
CFAMM00570661 ZINC09419327 Natural Product STOCK6S-30249
CFAMM00570674 ZINC05156095 Natural Product [(2Z)-2-(furan-2-ylmethylidene)-3-oxo-1-benzofuran-6-yl] 2-chlorobenzoate
CFAMM00570667 ZINC13759308 Natural Product AC1LZODJ
CFAMM00570680 ZINC02413785 Natural Product AC1LZXO0
CFAMM00570660 ZINC13787261 Natural Product AC1M0WW5
CFAMM00570673 ZINC02419033 Natural Product (2Z)-6-[(2,4-dichlorophenyl)methoxy]-2-(furan-2-ylmethylidene)-1-benzofuran-3-one
CFAMM00570666 ZINC13758472 Natural Product AC1LZILT
CFAMM00570679 ZINC05254611 Natural Product AC1M0NBL
CFAMM00570659 ZINC13778660 Natural Product AC1M0AWQ
CFAMM00570672 ZINC05179622 Natural Product (2Z)-6-[(2-chlorophenyl)methoxy]-2-(furan-2-ylmethylidene)-1-benzofuran-3-one
CFAMM00570665 ZINC12862437 Natural Product (Z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl furan-2-carboxylate
CFAMM00570678 ZINC13770148 Natural Product AC1M0YWC
CFAMM00570658 ZINC13778829 Natural Product AC1M0BM9
CFAMM00570671 ZINC02414848 Natural Product (2Z)-6-[(2-chloro-4-fluorophenyl)methoxy]-2-(furan-2-ylmethylidene)-1-benzofuran-3-one
CFAMM00570664 ZINC04184808 Natural Product 2-[(2E)-3-(2-chlorophenyl)prop-2-enoyl]-5-methoxyphenyl furan-2-carboxylate
CFAMM00570677 ZINC13768861 Natural Product AC1LZX67
CFAMM00570657 ZINC05156722 Natural Product [(2Z)-2-[(2-chloro-6-fluorophenyl)methylidene]-3-oxo-1-benzofuran-6-yl] furan-2-carboxylate
CFAMM00570670 ZINC02411794 Natural Product (2Z)-6-[2-(4-chlorophenyl)-2-oxoethoxy]-2-(furan-2-ylmethylidene)-1-benzofuran-3-one
CFAMM00570683 ZINC02441124 Natural Product AC1M0Y7R

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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