CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3497
Family Name 2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino[2,3-g]pyrido[2,1-a]isoquinolin-4(10H)-one NP (2,6-dimethoxyphenyl)(7-methylene-3,4,9,10-tetrahydro-2h-[1,4]dioxepino[2,3-g]isoquinolin-8(7h)-yl)methanone Family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00570738 Functional Category Natural Product
Superfamily Prelamin-A/C and Cellular tumor antigen p53 Binder Superfamily 4
Class Class 92

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Histamine H3 receptor Ligand A-349821 Family 49 228
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 2 6
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00... 5 14
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 1 5
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 1
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Putative NP ZINC20113153 Family 20 0
NP (e)-4-methoxy-6,6-dimethyl-5-(2-oxo-4-(2,6,6-trimethylcyclo... 131 0
Putative NP ZINC02127056 Family 4 1
9,10-dihydro-8H-pyrano[2,3-f][1,3]benzoxazin-9-ium-4-one NP ZI... 8 1
NP ((1r,4as,8as)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)octahydr... 3 3
6,7-dihydropyrimido[6,1-a]isoquinolin-4-one NP ZINC02112138 Fa... 10 0
Putative NP ZINC08791780 Family 3 0
Putative NP ZINC00519603 Family 8 1
Putative NP ZINC02424496 Family 5 0
8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-8-ium-3-one NP ZINC2... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00570738 ZINC04090839 Natural Product 2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino[2,3-g]pyrido[2,1-a]isoquinolin-4(10H)-one
CFAMM00570737 ZINC04090292 Natural Product (2,6-dimethoxyphenyl)(7-methylene-3,4,9,10-tetrahydro-2H-[1,4]dioxepino[2,3-g]isoquinolin-8(7H)-yl)methanone
CFAMM00570736 ZINC04090842 Natural Product 2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino[2,3-g]pyrido[2,1-a]isoquinolin-4(10H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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