CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3573
Family Name 8,10,10-trimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP (e)-10a-(3-(allyloxy)styryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1h)-one Family
No. of Seeds 14 No. of Other Members 0
Family Centroid CFAMM00570987 Functional Category Natural Product
Superfamily 4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one NP ZINC02127158 and 3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP ZINC02129938 Superfamily
Class Class 334

Cousin Family NamesSeedsMembers
Substance-K receptor Ligand MEN-14933 Family 13 154
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Transient receptor potential cation channel subfamily V member... 3 15
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9818603 f... 2 2
Acyl-CoA:cholesterol acyltransferase inhibitor [2,6-di(propan-... 1 0
4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one NP ZINC02... 37 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00570986 ZINC04000120 Natural Product (10aR)-10a-[(E)-2-(2-hexoxyphenyl)ethenyl]-8,10,10-trimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one
CFAMM00570993 ZINC02126796 Natural Product (10aR)-8,10,10-trimethyl-10a-[(E)-2-(3-prop-2-enoxyphenyl)ethenyl]-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one
CFAMM00570985 ZINC02128077 Natural Product (E)-10a-(2-(hexyloxy)styryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570992 ZINC02726722 Natural Product (E)-10a-(2,3-dimethoxystyryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570984 ZINC04000214 Natural Product AC1O7BD5
CFAMM00570991 ZINC04000166 Natural Product (E)-8,10,10-trimethyl-10a-(3-(pentyloxy)styryl)-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570983 ZINC02130238 Natural Product AC1LWUKT
CFAMM00570998 ZINC04000141 Natural Product (E)-10a-(2,5-dimethoxystyryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570990 ZINC02160695 Natural Product AC1LXU7A
CFAMM00570997 ZINC04000143 Natural Product (E)-10a-(2-butoxystyryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570989 ZINC02132102 Natural Product AC1LWX06
CFAMM00570996 ZINC04000180 Natural Product (E)-10a-(2,4-dimethoxystyryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
CFAMM00570988 ZINC02131081 Natural Product (10aR)-8,10,10-trimethyl-10a-[(E)-2-(3-pentoxyphenyl)ethenyl]-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one
CFAMM00570995 ZINC04000109 Natural Product (E)-10a-(3-(allyloxy)styryl)-8,10,10-trimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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