CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3630
Family Name 8'-fluoro-6'-methyl-2,3,4,5',6',9-hexahydrodispiro[beta-carboline-1,1'-pyrrolo[3,2,1-ij]quinoline-4',1''-cyclopentan]-2'-one NP 3-(3,4-dihydro-1h-pyrido[3,4-b]indol-2(9h)-yl)-1-(4-isopropylphenyl)pyrrolidine-2,5-dione Family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00571179 Functional Category Natural Product
Superfamily Prelamin-A/C and Cholinesterase Binder Superfamily 2
Class Class 173

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Growth hormone receptor Ligand EP-51216 Family 34 390
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
Somatostatin receptor type 4 and Somatostatin receptor type 5 ... 3 4
Nonstructural protein 1 and Lysine-specific demethylase 4E inh... 1 0
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 11 0
(S)-2-amino-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4... 1 0
(4aR,13bS,14aR)-3,4,4a,5,7,8,13,13b,14,14a-decahydro-5,14-etha... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00571179 ZINC14162429 Natural Product 8'-fluoro-6'-methyl-2,3,4,5',6',9-hexahydrodispiro[beta-carboline-1,1'-pyrrolo[3,2,1-ij]quinoline-4',1''-cyclopentan]-2'-one
CFAMM00571178 ZINC14162435 Natural Product 8'-fluoro-6'-methyl-2,3,4,5',6',9-hexahydrodispiro[beta-carboline-1,1'-pyrrolo[3,2,1-ij]quinoline-4',1''-cyclopentan]-2'-one
CFAMM00571177 ZINC14162432 Natural Product 8'-fluoro-6'-methyl-2,3,4,5',6',9-hexahydrodispiro[beta-carboline-1,1'-pyrrolo[3,2,1-ij]quinoline-4',1''-cyclopentan]-2'-one
CFAMM00571181 ZINC38830218 Natural Product 3-(3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)-1-(4-isopropylphenyl)pyrrolidine-2,5-dione
CFAMM00571180 ZINC14162438 Natural Product 10'-fluoro-7'-methyl-2'',3'',4'',9''-tetrahydrodispiro[cyclopentane-1,5'-[4]azatricyclo[6.3.1.0^{4,12}]dodecane-2',1''-pyrido[3,4-b]indole]-1'(11'),8'(12'),9'-trien-3'-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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