CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3633
Family Name Putative NP ZINC40310254 Family
No. of Seeds 74 No. of Other Members 1
Family Centroid CFAMM00571204 Functional Category Natural Product
Superfamily Histamine H3 receptor and Alpha-2A adrenergic receptor Binder Superfamily
Class Class 1671

Cousin Family NamesSeedsMembers
Eluxadoline family 4 85
Renin Inhibitor Enalkiren Family 56 44
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Type-2 angiotensin II receptor and Type-1A angiotensin II rece... 2 24
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Putative NP ZINC20112670 Family 20 1
propanoate NP ZINC40309138 Family 20 1
Putative NP ZINC40310111 Family 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00571204 ZINC20762392 Natural Product methyl (2S)-2-[[(4S)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571217 ZINC32123826 Natural Product dimethyl (2S)-2-[[(4R)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]butanedioate
CFAMM00571263 ZINC32124445 Natural Product methyl (2S)-2-[[(4S)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate
CFAMM00571191 ZINC20763168 Natural Product methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)acetate
CFAMM00571230 ZINC32124431 Natural Product methyl 4-[[(4R)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]butanoate
CFAMM00571243 ZINC20762045 Natural Product (2S)-methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylbutanoate
CFAMM00571197 ZINC32123785 Natural Product methyl (2S)-2-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-4-methylsulfanylbutanoate
CFAMM00571256 ZINC20761206 Natural Product (2S,3R)-methyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylpentanoate
CFAMM00571210 ZINC20762915 Natural Product (2S,3R)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylpentanoate
CFAMM00571223 ZINC40309254 Natural Product (2S)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-methylpentanoate
CFAMM00571236 ZINC32124517 Natural Product methyl (2S)-2-[[(4R)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-4-methylsulfanylbutanoate
CFAMM00571249 ZINC20761854 Natural Product (2S,3R)-methyl 2-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylpentanoate
CFAMM00571262 ZINC32124021 Natural Product methyl 3-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571203 ZINC20762173 Natural Product (2S)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571216 ZINC20762482 Natural Product methyl 2-[[(4R)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]acetate
CFAMM00571229 ZINC20761784 Natural Product methyl 2-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)acetate
CFAMM00571242 ZINC20763173 Natural Product methyl 2-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]acetate
CFAMM00571196 ZINC32123784 Natural Product (2S)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-(methylthio)butanoate
CFAMM00571255 ZINC20761201 Natural Product methyl (2S,3R)-2-[[(4S)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylpentanoate
CFAMM00571209 ZINC40309348 Natural Product (2S)-methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-methylpentanoate
CFAMM00571222 ZINC36369912 Natural Product (2S)-2-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571235 ZINC20762539 Natural Product methyl 2-[[(4R)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]acetate
CFAMM00571248 ZINC20763133 Natural Product (2S)-dimethyl 2-(4-(2-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)pentanedioate
CFAMM00571261 ZINC20762372 Natural Product (2S,3R)-methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylpentanoate
CFAMM00571202 ZINC20761849 Natural Product methyl (2S,3R)-2-[[(4S)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylpentanoate
CFAMM00571215 ZINC20761239 Natural Product methyl (2S)-2-[[(4R)-4-(2-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-4-methylsulfanylbutanoate
CFAMM00571228 ZINC20761891 Natural Product (2S)-methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571241 ZINC20762530 Natural Product dimethyl (2S)-2-[[(4R)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]pentanedioate
CFAMM00571195 ZINC20762525 Natural Product (2S)-dimethyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)pentanedioate
CFAMM00571208 ZINC20762910 Natural Product methyl (2S,3R)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylpentanoate
CFAMM00571221 ZINC32124086 Natural Product dimethyl (2S)-2-[[(4R)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]butanedioate
CFAMM00571234 ZINC32124511 Natural Product methyl 4-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)butanoate
CFAMM00571247 ZINC20763158 Natural Product methyl 2-[[(4R)-4-(2-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]acetate
CFAMM00571260 ZINC32124231 Natural Product (2S)-methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-(methylthio)butanoate
CFAMM00571201 ZINC20762500 Natural Product methyl (2S)-2-[[(4S)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571214 ZINC20763647 Natural Product (2S)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylbutanoate
CFAMM00571227 ZINC40309346 Natural Product methyl (2S)-2-[[(4S)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-4-methylpentanoate
CFAMM00571240 ZINC32124446 Natural Product (2S)-methyl 2-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571253 ZINC32124022 Natural Product methyl 3-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate
CFAMM00571194 ZINC32124512 Natural Product methyl 4-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]butanoate
CFAMM00571207 ZINC32123964 Natural Product (2S)-methyl 2-(4-(2,5-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-phenylpropanoate
CFAMM00571220 ZINC32124085 Natural Product (2S)-dimethyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)succinate
CFAMM00571233 ZINC20762478 Natural Product methyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)acetate
CFAMM00571246 ZINC20762040 Natural Product methyl (2S)-2-[[(4S)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571259 ZINC32124232 Natural Product methyl (2S)-2-[[(4R)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-4-methylsulfanylbutanoate
CFAMM00571200 ZINC20762397 Natural Product (2S)-methyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylbutanoate
CFAMM00571213 ZINC32124269 Natural Product dimethyl (2S)-2-[[(4R)-4-(2-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]butanedioate
CFAMM00571226 ZINC40310254 Natural Product (2S)-2-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-3-phenylpropanoate
CFAMM00571239 ZINC20762535 Natural Product methyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)acetate
CFAMM00571252 ZINC40310258 Natural Product (2S)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-3-phenylpropanoate
CFAMM00571193 ZINC40309252 Natural Product methyl (2S)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-4-methylpentanoate
CFAMM00571206 ZINC32124516 Natural Product (2S)-methyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-(methylthio)butanoate
CFAMM00571265 ZINC20763061 Natural Product (2S)-dimethyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)pentanedioate
CFAMM00571219 ZINC20761234 Natural Product (2S)-methyl 2-(4-(2-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-(methylthio)butanoate
CFAMM00571232 ZINC20762367 Natural Product methyl (2S,3R)-2-[[(4S)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylpentanoate
CFAMM00571199 ZINC20762900 Natural Product methyl (2S)-2-[[(4S)-4-(3-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate
CFAMM00571245 ZINC20763153 Natural Product methyl 2-(4-(2-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)acetate
CFAMM00571258 ZINC20763067 Natural Product dimethyl (2S)-2-[[(4R)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]pentanedioate
CFAMM00571225 ZINC20761789 Natural Product methyl 2-[[(4R)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]acetate
CFAMM00571212 ZINC32124268 Natural Product (2S)-dimethyl 2-(4-(2-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)succinate
CFAMM00571238 ZINC32124410 Natural Product methyl 3-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571251 ZINC20761972 Natural Product methyl (2S)-2-[[(4R)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-4-methylsulfanylbutanoate
CFAMM00571192 ZINC32123965 Natural Product methyl (2S)-2-[[(4R)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-phenylpropanoate
CFAMM00571205 ZINC20761967 Natural Product (2S)-methyl 2-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-4-(methylthio)butanoate
CFAMM00571264 ZINC20761886 Natural Product methyl (2S)-2-[[(4S)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate
CFAMM00571218 ZINC32123825 Natural Product (2S)-dimethyl 2-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)succinate
CFAMM00571231 ZINC32124430 Natural Product methyl 4-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)butanoate
CFAMM00571244 ZINC20762168 Natural Product methyl (2S)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate
CFAMM00571198 ZINC20762504 Natural Product (2S)-methyl 2-(4-(2,3-dimethoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)-3-methylbutanoate
CFAMM00571257 ZINC20763138 Natural Product dimethyl (2S)-2-[[(4R)-4-(2-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]pentanedioate
CFAMM00571211 ZINC20763643 Natural Product methyl (2S)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571224 ZINC36369911 Natural Product (2S)-2-[[(4S)-4-(2,5-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]-3-methylbutanoate
CFAMM00571250 ZINC20762905 Natural Product (2S)-methyl 2-(4-(3-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)propanoate
CFAMM00571237 ZINC32124411 Natural Product methyl 3-[[(4R)-4-(2,3-dimethoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-5-carbonyl]amino]propanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543