CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP3911
Family Name orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Family
No. of Seeds 22 No. of Other Members 0
Family Centroid CFAMM00572291 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Integrase Inhibitor L-708,906 Family 1 8
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
2-amino-3-methylpentanoate NP 2-((3-(4-fluorophenoxy)-4-oxo-4h... 13 2
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
4-(7-((2-amino-3-phenylpropanoyl)oxy)-5-hydroxy-4-oxo-4H-chrom... 3 0
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
Putative NP ZINC05155929 Family 6 0
Putative NP ZINC13787156 Family 4 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
bromobenzoate NP ZINC11865066 Family 6 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00572279 ZINC01447959 Natural Product ST50071256
CFAMM00572292 ZINC01321528 Natural Product 3-(2-methoxyphenyl)-2-methyl-4-oxo-4H-chromen-7-yl 2-chlorobenzoate
CFAMM00572285 ZINC01770985 Natural Product ST50071430
CFAMM00572278 ZINC01770979 Natural Product 3-(4-chlorophenyl)-4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl 4-fluorobenzoate
CFAMM00572291 ZINC01770967 Natural Product [3-(4-chlorophenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] benzoate
CFAMM00572284 ZINC01777088 Natural Product ST50071204
CFAMM00572277 ZINC01959521 Natural Product ST50071402
CFAMM00572290 ZINC01780034 Natural Product ST50071432
CFAMM00572283 ZINC01985471 Natural Product ST50071376
CFAMM00572276 ZINC01770973 Natural Product [3-(4-chlorophenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] 4-methoxybenzoate
CFAMM00572289 ZINC02436847 Natural Product ST50071253
CFAMM00572282 ZINC02244790 Natural Product ST50071632
CFAMM00572288 ZINC01780036 Natural Product 3-(2-methoxyphenyl)-4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl 4-chlorobenzoate
CFAMM00572275 ZINC01979546 Natural Product ST50071322
CFAMM00572281 ZINC02399741 Natural Product ST50071250
CFAMM00572294 ZINC02434853 Natural Product ST50071631
CFAMM00572274 ZINC02417737 Natural Product ST50071268
CFAMM00572287 ZINC01447990 Natural Product 3-(4-chlorophenyl)-4-oxo-2-(trifluoromethyl)-4H-chromen-7-yl cyclopropanecarboxylate
CFAMM00572280 ZINC01959507 Natural Product ST50071652
CFAMM00572293 ZINC01959518 Natural Product ST50071431
CFAMM00572273 ZINC02420684 Natural Product ST50071897
CFAMM00572286 ZINC02211101 Natural Product ST50071910

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27055 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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