CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP4151
Family Name 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate NP 2-methyl-2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indole-8-carboxylic Acid Hydrochloride Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00572874 Functional Category Natural Product
Superfamily MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801315 Superfamily
Class Class 3380

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Tubulin beta chain Inhibitor Isopropyl 3-(phenylthio)-1h-indol... 1 7
Metabotropic glutamate receptor 5 Ligand 6-phenylethynyl-nicot... 2 26
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
Putative NP ZINC15919780 Family 2 0
methyl 4-[(5Z)-5-(1H-indol-3-ylmethylidene)-4-oxo-2-sulfanylid... 1 0


External ID

Functional Category

Molecule Name

CFAMM00572875 ZINC14951238 Natural Product 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid
CFAMM00572874 ZINC02726205 Natural Product 2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carboxylic acid hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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