CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP420
Family Name Putative NP ZINC31158464 Family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00551224 Functional Category Natural Product
Superfamily Benzofurans Metabolite 4-Hydroxyphthalide Superfamily
Class Class 7497

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Agrimophol family 10 22
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Kynureninase Inhibitor 3-methoxydesaminokynurenine Family 1 1
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Endothelin-1 receptor Ligand PD156707 Family 41 211
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Phelli... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Arachidonate 5-lipoxygenase Inhibitor 4,5-dimethoxy-10h-anthra... 1 4
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Amine oxidase [flavin-containing] B inhibitor 5-(4,4,4-trifluo... 2 9
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Androgen receptor and Estrogen receptor ligand estradiol benzo... 1 29
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 0
Indoleamine 2,3-dioxygenase 1 inhibitor AGN-PC-04S2CP family 1 3
Benzofurans Metabolite 4-Hydroxyphthalide Family 1 1
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3
Acenes Metabolite Lacinilene C Family 2 3
Indenes and Isoindenes Metabolite Coixinden B Family 1 0
Naphthofurans Metabolite Pyrocurzerenone Family 1 9
Putative NP ZINC49600254 Family 8 2
Putative NP ZINC31165975 Family 4 0
2-benzoyl-3-(3,4-dimethoxyphenyl)-2-ethylcyclopropane-1,1-dica... 4 0
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
4H-1,3-benzodioxine-6-carboxylate NP ZINC07952017 Family 2 2
NP Ethyl 5-(tert-butyl)-3-oxo-8,9,10,11-tetrahydro-3h-benzofur... 1 0
2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate NP ZINC00132596... 4 2
NP (2r,3r,4s,5r,6s)-2-(acetoxymethyl)-6-(2-propionylphenoxy)te... 2 3
NP 4-(5-fluoro-3-methylbenzofuran-2-yl)-7,8-dihydrocyclopenta[... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00551223 ZINC02124520 Natural Product 2-butyl-5-methoxybenzene-1,3-dicarboxylate
CFAMM00551225 ZINC31158469 Natural Product 7-hydroxy-3-[(2S)-2-hydroxypropyl]-5-methylisochromen-1-one
CFAMM00551224 ZINC31158464 Natural Product 7-hydroxy-3-[(2R)-2-hydroxypropyl]-5-methylisochromen-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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