CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP4706
Family Name 1-benzofuran-3-one NP ZINC09486173 Family
No. of Seeds 33 No. of Other Members 0
Family Centroid CFAMM00574459 Functional Category Natural Product
Superfamily Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Squalene--hopene cyclase and Lanosterol synthase inhibitor R17... 1 22
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 11
NP Agn-pc-054n5h Family 5 0
Putative NP ZINC20357755 Family 11 0
2-(trifluoromethyl)chromen-4-one NP ZINC02418160 Family 7 0
6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC2... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00574467 ZINC08990946 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-[(4-methylpiperidin-1-ium-1-yl)methyl]-1-benzofuran-3-one
CFAMM00574480 ZINC02230941 Natural Product AC1LY08N
CFAMM00574460 ZINC13541106 Natural Product AC1M00BM
CFAMM00574473 ZINC09047546 Natural Product [(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-dipropylazanium
CFAMM00574486 ZINC05442911 Natural Product [(2Z)-2-[(4-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-dimethylazanium
CFAMM00574466 ZINC02330234 Natural Product (2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-7-(pyrrolidin-1-ium-1-ylmethyl)-1-benzofuran-3-one
CFAMM00574479 ZINC09577486 Natural Product benzyl-[[(2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl]-methylazanium
CFAMM00574459 ZINC09577459 Natural Product [(2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-butyl-methylazanium
CFAMM00574472 ZINC09420767 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-7-[[(3S,5S)-3,5-dimethylpiperidin-1-ium-1-yl]methyl]-6-hydroxy-1-benzofuran-3-one
CFAMM00574485 ZINC13682591 Natural Product [(2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-dipropylazanium
CFAMM00574465 ZINC09047822 Natural Product [(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-dibutylazanium
CFAMM00574478 ZINC05397876 Natural Product [(2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-dimethylazanium
CFAMM00574491 ZINC08992311 Natural Product (2Z)-7-(azepan-1-ium-1-ylmethyl)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-1-benzofuran-3-one
CFAMM00574471 ZINC09420766 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-7-[[(3S,5R)-3,5-dimethylpiperidin-1-ium-1-yl]methyl]-6-hydroxy-1-benzofuran-3-one
CFAMM00574484 ZINC09575758 Natural Product (2Z)-7-(azepan-1-ium-1-ylmethyl)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-1-benzofuran-3-one
CFAMM00574464 ZINC09575415 Natural Product [(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-diethylazanium
CFAMM00574477 ZINC13681775 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-[[(3S)-3-methylpiperidin-1-ium-1-yl]methyl]-1-benzofuran-3-one
CFAMM00574490 ZINC13655286 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-(piperidin-1-ium-1-ylmethyl)-1-benzofuran-3-one
CFAMM00574470 ZINC09576519 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-(pyrrolidin-1-ium-1-ylmethyl)-1-benzofuran-3-one
CFAMM00574483 ZINC22936634 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-7-[(4-ethylpiperazin-4-ium-1-yl)methyl]-6-hydroxy-1-benzofuran-3-one
CFAMM00574463 ZINC08991211 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-[[(2R)-2-methylpiperidin-1-ium-1-yl]methyl]-1-benzofuran-3-one
CFAMM00574476 ZINC02236062 Natural Product AC1LY70S
CFAMM00574489 ZINC09051389 Natural Product benzyl-[[(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl]-methylazanium
CFAMM00574482 ZINC09486173 Natural Product [(2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-bis(2-methylpropyl)azanium
CFAMM00574469 ZINC09420768 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-7-[[(3R,5R)-3,5-dimethylpiperidin-1-ium-1-yl]methyl]-6-hydroxy-1-benzofuran-3-one
CFAMM00574462 ZINC08991212 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-[[(2S)-2-methylpiperidin-1-ium-1-yl]methyl]-1-benzofuran-3-one
CFAMM00574475 ZINC02431430 Natural Product AC1M0KEZ
CFAMM00574488 ZINC09484064 Natural Product [(2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-diethylazanium
CFAMM00574468 ZINC09050232 Natural Product [(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-bis(2-methylpropyl)azanium
CFAMM00574481 ZINC13655026 Natural Product [(2Z)-2-[(5-bromo-2-methoxyphenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-butyl-methylazanium
CFAMM00574461 ZINC09047965 Natural Product benzyl-[[(2Z)-2-[(3-bromophenyl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl]-methylazanium
CFAMM00574474 ZINC13681772 Natural Product (2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-7-[[(3R)-3-methylpiperidin-1-ium-1-yl]methyl]-1-benzofuran-3-one
CFAMM00574487 ZINC09575586 Natural Product [(2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-3-oxo-1-benzofuran-7-yl]methyl-bis(2-methylpropyl)azanium

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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