CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP4724
Family Name 2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family
No. of Seeds 25 No. of Other Members 0
Family Centroid CFAMM00574751 Functional Category Natural Product
Superfamily 1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Furan-2-carboxylate and orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7-yl 2-chlorobenzoate Superfamily
Class Class 2438

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Peroxisome proliferator-activated receptor alpha and Peroxisom... 4 28
Free fatty acid receptor 1 ligand SureCN14018049 family 1 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 13
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
NP 3-(4-chlorophenyl)-4,9-dimethyl-7h-furo[2,3-f]chromen-7-one... 18 0
NP Ethyl 3-(4-bromophenyl)-7-((methylsulfonyl)oxy)-4-oxo-4h-ch... 9 1
NP 6-chloro-7-(2-(4-chlorophenyl)-2-oxoethoxy)-4-phenyl-2h-chr... 2 3
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP 3-(4-methoxyphenoxy)-4-oxo-4h-chromen-7-yl 4-bromobenzoate ... 13 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
1-benzofuran-3-one NP (z)-2-(4-chlorobenzylidene)-3-oxo-2,3-di... 27 0
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
8-methyl-4-(2-oxochromen-3-yl)chromen-2-one NP 7'-((2,6-dichlo... 3 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
orobenzoate NP 3-(2-methoxyphenyl)-2-methyl-4-oxo-4h-chromen-7... 22 0
Putative NP ZINC05155929 Family 6 0
Putative NP ZINC09486076 Family 56 0
Putative NP ZINC13787156 Family 4 0
Putative NP ZINC09305195 Family 19 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
1-benzofuran-3-one NP ZINC02423517 Family 24 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
1-benzofuran-3-one NP ZINC02424004 Family 22 0
Putative NP ZINC09051797 Family 10 0
NP 2-amino-7-[(2,6-dichlorophenyl)methoxy]-3-(4-methoxyphenyl)... 4 0
NP 3-(4-bromophenyl)-4-oxo-4h-chromen-7-yl 4-chlorobenzoate Fa... 17 0
Putative NP ZINC01135787 Family 3 0
NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0
Putative NP ZINC09517236 Family 5 0
bromobenzoate NP ZINC11865066 Family 6 0
Putative NP ZINC02417403 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00574759 ZINC02247926 Natural Product AC1LYJBY
CFAMM00574772 ZINC02667597 Natural Product 7-[(3,4-dichlorophenyl)methoxy]-3-(2-methoxyphenyl)chromen-4-one
CFAMM00574752 ZINC01782008 Natural Product 7-[(2,4-dichlorobenzyl)oxy]-3-(2-methoxyphenyl)-4H-chromen-4-one
CFAMM00574765 ZINC01940911 Natural Product ST50071418
CFAMM00574758 ZINC01447931 Natural Product 3-(4-chlorophenyl)-7-[2-(4-fluorophenyl)-2-oxoethoxy]chromen-4-one
CFAMM00574771 ZINC02252631 Natural Product AC1LYOX5
CFAMM00574764 ZINC01929476 Natural Product AC1LVIGT
CFAMM00574751 ZINC02419824 Natural Product 7-[(2-chloro-6-fluorophenyl)methoxy]-3-(4-chlorophenyl)chromen-4-one
CFAMM00574757 ZINC01959503 Natural Product ST50071421
CFAMM00574770 ZINC02420951 Natural Product 7-[(2-chloro-4-fluorophenyl)methoxy]-3-(4-chlorophenyl)chromen-4-one
CFAMM00574750 ZINC02666276 Natural Product ST50071105
CFAMM00574763 ZINC01447918 Natural Product AC1LU7OK
CFAMM00574756 ZINC01915154 Natural Product 7-[(2-chloro-6-fluorobenzyl)oxy]-3-(4-chlorophenyl)-2-(trifluoromethyl)-4H-chromen-4-one
CFAMM00574769 ZINC02411359 Natural Product ST50071544
CFAMM00574762 ZINC02666300 Natural Product 7-[(2,6-dichlorophenyl)methoxy]-3-phenyl-2-(trifluoromethyl)chromen-4-one
CFAMM00574755 ZINC02414186 Natural Product ST50071581
CFAMM00574768 ZINC11865234 Natural Product ST50472147
CFAMM00574761 ZINC02256661 Natural Product AC1LYTJI
CFAMM00574774 ZINC01815168 Natural Product AC1LV2HK
CFAMM00574754 ZINC02420061 Natural Product ST50071476
CFAMM00574767 ZINC02248124 Natural Product AC1LYJL4
CFAMM00574760 ZINC01959218 Natural Product ST50071274
CFAMM00574773 ZINC02667596 Natural Product ST50472132
CFAMM00574753 ZINC02402237 Natural Product ST50472108
CFAMM00574766 ZINC11865232 Natural Product ST50472126

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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