CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP4803
Family Name 2-(trifluoromethyl)chromen-4-one NP ZINC02418160 Family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00575310 Functional Category Natural Product
Superfamily Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Squalene--hopene cyclase and Lanosterol synthase inhibitor R17... 1 22
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 11
1-benzofuran-3-one NP ZINC09486173 Family 33 0
NP Agn-pc-054n5h Family 5 0
Putative NP ZINC20357755 Family 11 0
6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC2... 7 0


External ID

Functional Category

Molecule Name

CFAMM00575312 ZINC20412355 Natural Product AGN-PC-05FG3E
CFAMM00575311 ZINC09282031 Natural Product 3-(2-bromophenoxy)-7-hydroxy-8-[[(3S)-3-methylpiperidin-1-ium-1-yl]methyl]-2-(trifluoromethyl)chromen-4-one
CFAMM00575310 ZINC09282030 Natural Product 3-(2-bromophenoxy)-7-hydroxy-8-[[(3R)-3-methylpiperidin-1-ium-1-yl]methyl]-2-(trifluoromethyl)chromen-4-one
CFAMM00575309 ZINC20412351 Natural Product AGN-PC-05FG3D
CFAMM00575308 ZINC02418160 Natural Product AC1NW7XH
CFAMM00575307 ZINC06498958 Natural Product AGN-PC-05XR7D
CFAMM00575313 ZINC00934295 Natural Product 3-(2-bromophenoxy)-7-hydroxy-8-(piperidin-1-ium-1-ylmethyl)-2-(trifluoromethyl)chromen-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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