CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP4805
Family Name 6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC20519285 Family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00575322 Functional Category Natural Product
Superfamily Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor 2-(2-bromophenyl)-5,7-dihydroxy-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)chromen-4-one Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Squalene--hopene cyclase and Lanosterol synthase inhibitor R17... 1 22
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 11
NP 1,3,8-trihydroxy-6-methyl-2-(morpholinomethyl)anthracene-9,... 2 0
1-benzofuran-3-one NP ZINC09486173 Family 33 0
NP Agn-pc-054n5h Family 5 0
1-benzofuran-3-one NP ZINC02445091 Family 23 0
Putative NP ZINC20357755 Family 11 0
2-(trifluoromethyl)chromen-4-one NP ZINC02418160 Family 7 0


External ID

Functional Category

Molecule Name

CFAMM00575323 ZINC20518225 Natural Product AC1LXNZM
CFAMM00575322 ZINC20519285 Natural Product AC1M0N1I
CFAMM00575321 ZINC20650720 Natural Product STOCK6S-42380
CFAMM00575320 ZINC08990216 Natural Product STOCK6S-39418
CFAMM00575326 ZINC02217471 Natural Product AC1LXI94
CFAMM00575325 ZINC20503982 Natural Product AC1LXL0J
CFAMM00575324 ZINC20519089 Natural Product AC1LYE62

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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