CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP584
Family Name NP 3-((3a's,6a'r)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro-5-methyl-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'h-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)propanamide Family
No. of Seeds 32 No. of Other Members 0
Family Centroid CFAMM00551978 Functional Category Natural Product
Superfamily Retinal dehydrogenase 1 and Beta-lactamase inhibitor CHEMBL1563150 Superfamily
Class Class 6782

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Endothelin B receptor and Endothelin-1 receptor ligand SureCN8... 6 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00551966 ZINC15968020 Natural Product 2-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551982 ZINC15959620 Natural Product 3-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551947 ZINC15959861 Natural Product 3-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551975 ZINC15967762 Natural Product 2-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551989 ZINC15959940 Natural Product 3-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551959 ZINC15959938 Natural Product 3-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551981 ZINC15967741 Natural Product 3-[(1S,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551946 ZINC15959619 Natural Product 3-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551974 ZINC15968018 Natural Product 2-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551988 ZINC15968837 Natural Product 3-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551957 ZINC15969405 Natural Product 2-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551980 ZINC15967742 Natural Product 3-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551945 ZINC15959618 Natural Product 3-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro-5-methyl-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)propanamide
CFAMM00551973 ZINC15969407 Natural Product 2-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551987 ZINC15968835 Natural Product 3-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551954 ZINC15969404 Natural Product 2-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-5-chloro-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)acetamide
CFAMM00551979 ZINC15967744 Natural Product 3-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551944 ZINC15967759 Natural Product 2-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551972 ZINC15967761 Natural Product 2-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro-5-methyl-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)acetamide
CFAMM00551986 ZINC15959939 Natural Product 3-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551951 ZINC15959617 Natural Product 3-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551978 ZINC15968014 Natural Product 2-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)acetamide
CFAMM00551971 ZINC15969409 Natural Product 2-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551985 ZINC15968833 Natural Product 3-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanamide
CFAMM00551949 ZINC15968832 Natural Product 3-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-7-chloro-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)propanamide
CFAMM00551977 ZINC15967746 Natural Product 3-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551993 ZINC15959862 Natural Product 3-[(1S,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551970 ZINC15967764 Natural Product 2-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-5'-methyl-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551983 ZINC15959937 Natural Product 3-((3a'S,6a'R)-5'-(benzo[d][1,3]dioxol-5-ylmethyl)-5-chloro-2,4',6'-trioxo-3',3a',4',5',6',6a'-hexahydro-2'H-spiro[indoline-3,1'-pyrrolo[3,4-c]pyrrol]-3'-yl)propanamide
CFAMM00551976 ZINC15968016 Natural Product 2-[(1R,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-7'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]acetamide
CFAMM00551948 ZINC15959860 Natural Product 3-[(1S,3R,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate
CFAMM00551990 ZINC15959863 Natural Product 3-[(1R,3S,3aR,6aS)-5-(1,3-benzodioxol-5-ylmethyl)-5'-chloro-2',4,6-trioxospiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]-1-yl]propanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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