CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP5884
Family Name 2,4-bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylate NP ZINC00028447 Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00581296 Functional Category Natural Product
Superfamily Tyrosinase and DNA polymerase Binder Superfamily
Class Class 2550

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Tyrosine 3-monooxygenase Inhibitor L-tyrosine Family 4 36
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand Dienestrol Family 35 440
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
DNA polymerase Inhibitor 3alpha-o-trans-p-coumaroyl-7-labden-1... 1 13
Aromatase inhibitor (3R,4R)-4-benzyl-3-[(3-hydroxyphenyl)methy... 1 10
Prelamin-A/C inhibitor CHEMBL1495780 family 1 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
G2/mitotic-specific cyclin-B1 and Cyclin-dependent kinase 1 in... 2 8
NS5B protein inhibitor SureCN3988565 family 2 4
Glutamate carboxypeptidase 2 inhibitor 2-[(3-hydroxyphenyl)met... 1 0
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0
Putative NP ZINC03197541 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00581296 ZINC00028447 Natural Product 2,4-bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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