CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP605
Family Name NP N-(1h-indol-6-yl)-3-(4-methoxy-1h-indol-1-yl)propanamide Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00552235 Functional Category Natural Product
Superfamily Melatonin receptor type 1A and Melatonin receptor type 1B Binder Superfamily 4
Class Class 3075

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
DNA Binder Elliptinium Acetate Family 11 116
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Apricoxib family 8 77
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Platelet-derived growth factor receptor alpha and Platelet-der... 2 14
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Casein kinase I isoform gamma-2 and Casein kinase I isoform de... 5 2
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 1 2
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Protein kinase C theta type and Protein kinase C delta type in... 10 7
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Coagulation factor VII and Tissue factor inhibitor 5-azaindole... 4 3
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 0
Putative NP ZINC40309500 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00552236 ZINC62001415 Natural Product N-(1H-indol-6-yl)-3-(4-methoxy-1H-indol-1-yl)propanamide
CFAMM00552228 ZINC62001540 Natural Product N-(1H-indol-6-yl)-2-(4-methoxy-1H-indol-1-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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