CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name NP 1-(3-hydroxyphenyl)-3-(1-methyl-1h-indol-3-yl)pyrrolidine-2,5-dione Family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00552659 Functional Category Natural Product
Superfamily Androgen receptor and Histone deacetylase Binder Superfamily
Class Class 456

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 1 1
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8


External ID

Functional Category

Molecule Name

CFAMM00552660 ZINC02130179 Natural Product 1-(3-hydroxyphenyl)-3-(1-propyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CFAMM00552659 ZINC00490605 Natural Product 1-(3-hydroxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione
CFAMM00552662 ZINC02138613 Natural Product 3-(1-butyl-1H-indol-3-yl)-1-(3-hydroxyphenyl)pyrrolidine-2,5-dione
CFAMM00552661 ZINC00490904 Natural Product 1-(2-hydroxyphenyl)-3-(1-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



116236 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543