CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP655
Family Name Putative NP ZINC20113153 Family
No. of Seeds 20 No. of Other Members 0
Family Centroid CFAMM00552926 Functional Category Natural Product
Superfamily 1-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-9-yl)ethanone NP 1-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-9-yl)ethanone and 5-[3-[(3-tert-butyl-6,7,8,9-tetrahydrodibenzofuran-2-yl)oxy]prop-1-ynyl]-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline NP ZINC20113915 Superfamily
Class Class 621

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00... 5 14
NP (e)-4-methoxy-6,6-dimethyl-5-(2-oxo-4-(2,6,6-trimethylcyclo... 131 0
NP ((1r,4as,8as)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)octahydr... 3 3
Putative NP ZINC08791780 Family 3 0
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00552929 ZINC01815970 Natural Product AC1LV30Q
CFAMM00552920 ZINC20111945 Natural Product 1-[(2R)-1,1,2,3,3,6-hexamethyl-2H-inden-5-yl]-2-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]ethanone
CFAMM00552911 ZINC20111915 Natural Product AC1O6SYP
CFAMM00552928 ZINC01815971 Natural Product 5-(2-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2-oxoethyl)-4-methoxy-6,6-dimethyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide
CFAMM00552919 ZINC20111943 Natural Product AC1O6SYV
CFAMM00552910 ZINC20111917 Natural Product 1-[(6S)-3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl]-2-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]ethanone
CFAMM00552926 ZINC01280060 Natural Product AC1LQLV4
CFAMM00552917 ZINC01815969 Natural Product AC1LV30O
CFAMM00552909 ZINC20111974 Natural Product 1-(6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)-2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)ethanone
CFAMM00552925 ZINC01280061 Natural Product AC1LQLV7
CFAMM00552916 ZINC01836880 Natural Product AC1LUMU2
CFAMM00552908 ZINC20111972 Natural Product AC1LXFGN
CFAMM00552924 ZINC01280062 Natural Product 5-(2-(1,1,2,3,3,6-hexamethyl-2,3-dihydro-1H-inden-5-yl)-2-oxoethyl)-4-methoxy-6,6-dimethyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide
CFAMM00552915 ZINC20759384 Natural Product (2S)-5,6-dimethoxy-2-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2,3-dihydroinden-1-one
CFAMM00552907 ZINC20113153 Natural Product AC1LX03Q
CFAMM00552923 ZINC01280063 Natural Product AC1LQLVD
CFAMM00552914 ZINC01836881 Natural Product 5-(2-(6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)-2-oxoethyl)-4-methoxy-6,6-dimethyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide
CFAMM00552930 ZINC01815972 Natural Product AC1LV30U
CFAMM00552922 ZINC20759376 Natural Product (2S)-5,6-dimethoxy-2-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2,3-dihydroinden-1-one
CFAMM00552912 ZINC20113154 Natural Product 2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543