CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP695
Family Name Putative NP ZINC12858318 Family
No. of Seeds 42 No. of Other Members 0
Family Centroid CFAMM00553355 Functional Category Natural Product
Superfamily 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 38

Cousin Family NamesSeedsMembers
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
Putative NP ZINC12660125 Family 8 0
7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline NP ZINC33345333... 21 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00553387 ZINC20113168 Natural Product (NE)-N-[2-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-1-(4-methylphenyl)ethylidene]hydroxylamine
CFAMM00553353 ZINC20111933 Natural Product (Z)-1-(4-fluorophenyl)-2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)ethanone oxime
CFAMM00553366 ZINC06262261 Natural Product (NE)-N-[1-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6-methyl-3-(3-methylbut-2-enyl)hept-5-en-2-ylidene]hydroxylamine
CFAMM00553380 ZINC34871335 Natural Product (NE)-N-[(3E)-1-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-5,5,8-trimethylnona-3,7-dien-2-ylidene]hydroxylamine
CFAMM00553359 ZINC33915881 Natural Product (NZ)-N-[2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(4R)-4-(4-methylpent-3-enyl)cyclohexen-1-yl]ethylidene]hydroxylamine
CFAMM00553372 ZINC36368126 Natural Product (NE)-N-[(E)-1-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-4-[(1R)-2,6,6-trimethylcyclohex-2-en-1-yl]but-3-en-2-ylidene]hydroxylamine
CFAMM00553386 ZINC20111987 Natural Product (Z)-1-(benzo[d][1,3]dioxol-5-yl)-2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)ethanone oxime
CFAMM00553352 ZINC33957518 Natural Product (NE)-N-[2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(1S)-4-methylcyclohex-3-en-1-yl]ethylidene]hydroxylamine
CFAMM00553365 ZINC06262260 Natural Product (NE)-N-[1-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6-methyl-3-(3-methylbut-2-enyl)hept-5-en-2-ylidene]hydroxylamine
CFAMM00553379 ZINC20113732 Natural Product AC1NVB6X
CFAMM00553394 ZINC32110853 Natural Product (NZ)-N-[1-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]propan-2-ylidene]hydroxylamine
CFAMM00553358 ZINC20612408 Natural Product (NE)-N-[1-(4-bromophenyl)-2-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]ethylidene]hydroxylamine
CFAMM00553371 ZINC36368124 Natural Product (NE)-N-[(E)-1-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-4-[(1R)-2,6,6-trimethylcyclohex-2-en-1-yl]but-3-en-2-ylidene]hydroxylamine
CFAMM00553385 ZINC20111985 Natural Product AC1OECXQ
CFAMM00553351 ZINC20111931 Natural Product AC1OECWQ
CFAMM00553364 ZINC04030013 Natural Product AC1OEET5
CFAMM00553378 ZINC20612410 Natural Product (Z)-1-(4-bromophenyl)-2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)ethanone oxime
CFAMM00553393 ZINC32110851 Natural Product (NZ)-N-[1-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]propan-2-ylidene]hydroxylamine
CFAMM00553357 ZINC12858318 Natural Product (NZ)-N-[2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(4S)-4-(4-methylpent-3-enyl)cyclohexen-1-yl]ethylidene]hydroxylamine
CFAMM00553370 ZINC05727745 Natural Product (NE)-N-[1-[(4R)-2,2-dimethyloxan-4-yl]-2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]ethylidene]hydroxylamine
CFAMM00553384 ZINC20411371 Natural Product AC1NU2X6
CFAMM00553350 ZINC05726867 Natural Product (NE)-N-[1-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3-methylbutan-2-ylidene]hydroxylamine
CFAMM00553363 ZINC04030014 Natural Product (NZ)-N-[1-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6-methylhept-5-en-2-ylidene]hydroxylamine
CFAMM00553376 ZINC08917797 Natural Product (NZ)-N-[2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(4R)-4-(4-methylpent-3-enyl)cyclohexen-1-yl]ethylidene]hydroxylamine
CFAMM00553391 ZINC20411776 Natural Product (NE)-N-[2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(1R)-4-methylcyclohex-3-en-1-yl]ethylidene]hydroxylamine
CFAMM00553356 ZINC20113729 Natural Product (E)-3-ethoxy-4-((3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)prop-2-yn-1-yl)oxy)benzaldehyde oxime
CFAMM00553383 ZINC20113167 Natural Product 2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-1-(p-tolyl)ethanone oxime
CFAMM00553369 ZINC05727744 Natural Product (NE)-N-[1-[(4R)-2,2-dimethyloxan-4-yl]-2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]ethylidene]hydroxylamine
CFAMM00553362 ZINC20411362 Natural Product (NE)-N-[1-(6-tert-butyl-1,1-dimethyl-2,3-dihydroinden-4-yl)-2-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]ethylidene]hydroxylamine
CFAMM00553375 ZINC36032934 Natural Product (2Z,3E)-1-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-5,5,8-trimethylnona-3,7-dien-2-one oxime
CFAMM00553389 ZINC20411770 Natural Product (NE)-N-[2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(1R)-4-methylcyclohex-3-en-1-yl]ethylidene]hydroxylamine
CFAMM00553355 ZINC05726866 Natural Product (NE)-N-[1-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3-methylbutan-2-ylidene]hydroxylamine
CFAMM00553368 ZINC05727749 Natural Product (NE)-N-[1-[(4S)-2,2-dimethyloxan-4-yl]-2-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]ethylidene]hydroxylamine
CFAMM00553382 ZINC61992897 Natural Product (NE)-N-[(E)-1-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-4-[(1S)-2,6,6-trimethylcyclohex-2-en-1-yl]but-3-en-2-ylidene]hydroxylamine
CFAMM00553361 ZINC08917796 Natural Product (NZ)-N-[2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(4S)-4-(4-methylpent-3-enyl)cyclohexen-1-yl]ethylidene]hydroxylamine
CFAMM00553374 ZINC61996978 Natural Product (NE)-N-[(5E)-1-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,10-dimethyl-3-methylideneundeca-5,9-dien-2-ylidene]hydroxylamine
CFAMM00553388 ZINC61992898 Natural Product (NE)-N-[(E)-1-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-4-[(1S)-2,6,6-trimethylcyclohex-2-en-1-yl]but-3-en-2-ylidene]hydroxylamine
CFAMM00553354 ZINC33586942 Natural Product (2Z,5E)-1-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,10-dimethyl-3-methyleneundeca-5,9-dien-2-one oxime
CFAMM00553367 ZINC05727748 Natural Product (NE)-N-[1-[(4S)-2,2-dimethyloxan-4-yl]-2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]ethylidene]hydroxylamine
CFAMM00553381 ZINC20411374 Natural Product (Z)-1,1,1-trifluoro-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)propan-2-one oxime
CFAMM00553360 ZINC20411365 Natural Product (Z)-1-(6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)-2-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)ethanone oxime
CFAMM00553373 ZINC33918778 Natural Product (NE)-N-[2-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-1-[(1S)-4-methylcyclohex-3-en-1-yl]ethylidene]hydroxylamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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