CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP790
Family Name NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl Dimethylcarbamate Family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00554454 Functional Category Natural Product
Superfamily diethylcarbamate NP 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2h-chromen-7-yl Dimethylcarbamate and ethylcarbamate NP 6-chloro-2,2'-dioxo-2h,2'h-[3,4'-bichromen]-7'-yl Dimethylcarbamate Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Endothelin-1 receptor Ligand PD156707 Family 41 211
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-deh... 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Putative NP ZINC02398203 Family 1 0
1,3-dimethylcyclohepta[c]furan-8-one NP 6-(4-hydroxy-3-iodo-5-... 13 1
NP Ethyl 3-(4-bromophenyl)-7-((methylsulfonyl)oxy)-4-oxo-4h-ch... 9 1
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
NP (z)-2-((2-methyl-2h-chromen-3-yl)methylene)-3-oxo-2,3-dihyd... 74 1
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0
NP 4-(2,3,4-trimethoxyphenyl)-3,4-dihydro-2h-benzo[g]chromene-... 2 1
benzenesulfonate NP (z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-... 26 0
4-oxochromene-2-carboxylate NP Ethyl 3-(7-(2-(4-bromophenyl)-2... 10 1
NP Ethyl 7-((2-chlorobenzoyl)oxy)-3-(2-methoxyphenyl)-4-oxo-4h... 37 1
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3
Putative NP ZINC09486076 Family 56 0
bromobenzoate NP ZINC09346025 Family 20 0
1-benzofuran-3-one NP ZINC02367988 Family 9 0
benzenesulfonate NP ZINC09051160 Family 47 2
Putative NP ZINC02424323 Family 24 0
NP Af-399/42316321 Family 7 0
2-(trifluoromethyl)chromen-4-one NP ZINC01929476 Family 25 0
Putative NP ZINC02424496 Family 5 0
Putative NP ZINC09051797 Family 10 0
Putative NP ZINC09306352 Family 7 0
Putative NP ZINC09575270 Family 7 0
Putative NP ZINC01135787 Family 3 0
Putative NP ZINC09517236 Family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00554461 ZINC12861887 Natural Product (Z)-2-(3,4-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl dimethylcarbamate
CFAMM00554454 ZINC04339913 Natural Product [2-methoxy-4-[(Z)-(6-methoxy-3-oxo-1-benzofuran-2-ylidene)methyl]phenyl] N,N-dimethylcarbamate
CFAMM00554460 ZINC12636986 Natural Product (Z)-3-oxo-2-(3,4,5-trimethoxybenzylidene)-2,3-dihydrobenzofuran-6-yl dimethylcarbamate
CFAMM00554453 ZINC12662641 Natural Product (Z)-3-oxo-2-(2,3,4-trimethoxybenzylidene)-2,3-dihydrobenzofuran-6-yl dimethylcarbamate
CFAMM00554459 ZINC12662851 Natural Product (Z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl dimethylcarbamate
CFAMM00554458 ZINC06662909 Natural Product [(2Z)-2-[(3,4-dimethoxyphenyl)methylidene]-4-methyl-3-oxo-1-benzofuran-6-yl] N,N-dimethylcarbamate
CFAMM00554457 ZINC06755008 Natural Product [(2Z)-4-methyl-3-oxo-2-[(2,3,4-trimethoxyphenyl)methylidene]-1-benzofuran-6-yl] N,N-dimethylcarbamate
CFAMM00554456 ZINC06758543 Natural Product [(2Z)-4-methyl-3-oxo-2-[(3,4,5-trimethoxyphenyl)methylidene]-1-benzofuran-6-yl] N,N-dimethylcarbamate
CFAMM00554455 ZINC06167240 Natural Product (Z)-2-(benzo[d][1,3]dioxol-5-ylmethylene)-7-methyl-3-oxo-2,3-dihydrobenzofuran-6-yl dimethylcarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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