CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 3-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)amino]propanoate NP Methyl 3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamido)propanoate Family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00555066 Functional Category Natural Product
Superfamily Angiotensin-converting enzyme Inhibitor Moexipril Superfamily
Class Class 92

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand DA-5018 Family 14 73
D(3) dopamine receptor Ligand U-99194A Family 7 33
Ivabradine family 1 11
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 8 4
Motilin receptor and Growth hormone secretagogue receptor type... 1 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (E)-... 1 0
1,3-diazaadamantan-6-one NP ZINC19323291 Family 15 0
NP (z)-n-((4-(3,4-dimethoxyphenyl)tetrahydro-2h-pyran-4-yl)met... 3 2
NP N-(3,4-dimethoxyphenethyl)-2-(2-(hydroxymethyl)-5-methoxy-4... 1 0
Putative NP ZINC19322380 Family 2 2
Putative NP ZINC13119705 Family 3 0
1,3-diazaadamantan-6-ol NP ZINC19320140 Family 16 0
1,4,4a,5,6,8a-hexahydropyrimido[4,5-d]pyrimidine-2,7-dione NP ... 12 0
Putative NP ZINC04287792 Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00555067 ZINC08879315 Natural Product AGN-PC-05YH7I
CFAMM00555066 ZINC12894305 Natural Product methyl 3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxamido)propanoate
CFAMM00555065 ZINC08764247 Natural Product 6,7-dimethoxy-N-(3-((2-methoxybenzyl)amino)-3-oxopropyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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