CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP876
Family Name Putative NP ZINC04043753 Family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00555153 Functional Category Natural Product
Superfamily Muscleblind-like protein 1 and Tyrosyl-DNA phosphodiesterase 1 Binder Superfamily 3
Class Class 366

Cousin Family NamesSeedsMembers
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Lipoprotein lipase Inhibitor Gemfibrozil Family 1 28
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Ipriflavone family 62 2480
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Kinesin-like protein KIF11 inhibitor 2-amino-5-(4-methoxypheny... 1 4
Estrogen receptor beta and Estrogen receptor ligand SureCN4017... 3 5
Histone deacetylase 2 and Histone deacetylase 8 inhibitor AC1L... 2 2
Free fatty acid receptor 1 ligand 3-[4-[2-[2-(cyanomethoxy)phe... 1 2
Thioredoxin glutathione reductase and Beta-lactamase inhibitor... 1 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
NS5B protein inhibitor SureCN3988565 family 2 4
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Benzoxepines Metabolite 4,5-Dihydro-1-benzoxepin-3(2H)-one Family 1 2
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
4-ethenyl-4,10-dimethyl-2-(2-methylprop-1-enyl)-2,3-dihydropyr... 3 1
benzofuran-2-one NP 5-hydroxybenzofuran-2(3h)-one Family 1 0
2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate NP ZINC00132596... 4 2
Putative NP ZINC04029250 Family 6 2
3-pentyl-5-(phenoxymethyl)oxolan-2-one NP ZINC02116245 Family 4 0
NP Chemdiv1 023678 Family 4 3
2-[(3,4-dimethoxyphenyl)methyl]propanedioate NP 4aji Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00555164 ZINC00201893 Natural Product 2-[(4S)-4-(2-methoxyphenyl)-2,2-dimethyloxan-4-yl]acetate
CFAMM00555157 ZINC04043750 Natural Product 2-[(2S,4S)-4-(2-methoxyphenyl)-2-propan-2-yloxan-4-yl]acetate
CFAMM00555163 ZINC00201890 Natural Product AC1OCE7N
CFAMM00555156 ZINC04043753 Natural Product AC1O7AUL
CFAMM00555155 ZINC04043759 Natural Product AC1OELEE
CFAMM00555154 ZINC00159043 Natural Product (3S)-3,4-dihydro-2H-chromene-3-carboxylate
CFAMM00555153 ZINC02549250 Natural Product AC1M12GI
CFAMM00555152 ZINC00159041 Natural Product (3R)-3,4-dihydro-2H-chromene-3-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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