CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 2-benzoyl-3-(3,4-dimethoxyphenyl)-2-ethylcyclopropane-1,1-dicarboxylate NP ZINC01087771 Family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00555257 Functional Category Natural Product
Superfamily Prostaglandin G/H synthase 2 and CGMP-dependent protein kinase Binder Superfamily
Class Class 543

Cousin Family NamesSeedsMembers
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Endothelin-1 receptor Ligand PD156707 Family 41 211
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Cocaine esterase and Liver carboxylesterase 1 inhibitor 2-Chlo... 1 5
Putative NP ZINC31158464 Family 3 5
2-[(3,4-dimethoxyphenyl)methyl]propanedioate NP 4aji Family 1 0
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3


External ID

Functional Category

Molecule Name

CFAMM00555259 ZINC01087772 Natural Product AC1LOWPW
CFAMM00555258 ZINC01087771 Natural Product AC1LOWPU
CFAMM00555257 ZINC01087770 Natural Product AC1LOWPS
CFAMM00555260 ZINC01087773 Natural Product dimethyl 2-benzoyl-3-(3,4-dimethoxyphenyl)-2-ethylcyclopropane-1,1-dicarboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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