CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP910
Family Name 1,3-dimethylcyclohepta[c]furan-8-one NP 6-(4-hydroxy-3-iodo-5-methoxyphenyl)-8-methoxy-1,3-dimethyl-4h-cyclohepta[c]furan-4-one Family
No. of Seeds 13 No. of Other Members 1
Family Centroid CFAMM00555604 Functional Category Natural Product
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5-diphenyl-furan-3-yl)-phenyl-methanone Superfamily
Class Class 1672

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Endothelin-1 receptor Ligand PD156707 Family 41 211
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Cocaine esterase and Liver carboxylesterase 1 inhibitor 2-Chlo... 1 5
Platelet-activating factor receptor ligand (2S,3R,3aS)-2-(3,4-... 2 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
NP (z)-2-(2,3-dimethoxybenzylidene)-3-oxo-2,3-dihydrobenzofura... 9 0
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-methyl-... 2 0
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00555606 ZINC01106318 Natural Product 8-ethoxy-6-(4-hydroxy-3-iodo-5-methoxyphenyl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555612 ZINC00285889 Natural Product 6-(benzo[d][1,3]dioxol-5-yl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555611 ZINC00111991 Natural Product 6-(4-hydroxy-3-methoxyphenyl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555604 ZINC00842903 Natural Product 6-(3,4-dimethoxyphenyl)-8-ethoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555610 ZINC00277989 Natural Product 6-(benzo[d][1,3]dioxol-5-yl)-8-ethoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555616 ZINC00519624 Natural Product 6-(benzo[d][1,3]dioxol-5-yl)-8-hydroxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555603 ZINC02155901 Natural Product 6-(3-iodo-4,5-dimethoxyphenyl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555609 ZINC01833039 Natural Product 2-(4-(8-ethoxy-1,3-dimethyl-4-oxo-4H-cyclohepta[c]furan-6-yl)-2-methoxyphenoxy)acetonitrile
CFAMM00555615 ZINC00892069 Natural Product 8-ethoxy-1,3-dimethyl-6-(3,4,5-trimethoxyphenyl)-4H-cyclohepta[c]furan-4-one
CFAMM00555608 ZINC00313124 Natural Product 6-(3,4-dimethoxyphenyl)-8-hydroxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555614 ZINC02101785 Natural Product 8-hydroxy-1,3-dimethyl-6-(3,4,5-trimethoxyphenyl)-4H-cyclohepta[c]furan-4-one
CFAMM00555607 ZINC01106319 Natural Product 6-(4-hydroxy-3-iodo-5-methoxyphenyl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00555613 ZINC02100311 Natural Product 8-ethoxy-6-(3-iodo-4,5-dimethoxyphenyl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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