CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP943
Family Name 4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one NP ZINC02127158 Family
No. of Seeds 37 No. of Other Members 0
Family Centroid CFAMM00556017 Functional Category Natural Product
Superfamily 4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one NP ZINC02127158 and 3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP ZINC02129938 Superfamily
Class Class 334

Cousin Family NamesSeedsMembers
Substance-K receptor Ligand MEN-14933 Family 13 154
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Transient receptor potential cation channel subfamily V member... 3 15
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9818603 f... 2 2
Menin and Histone-lysine N-methyltransferase 2A inhibitor CHEM... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor [2,6-di(propan-... 1 0
8,10,10-trimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP... 14 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00555986 ZINC02115778 Natural Product AC1LXD8T
CFAMM00556001 ZINC02126026 Natural Product (E)-7-ethyl-9a-(4-methoxystyryl)-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556016 ZINC04000206 Natural Product (E)-9a-(2,3-dimethoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555993 ZINC02136148 Natural Product AC1LX1OO
CFAMM00556007 ZINC02120197 Natural Product (E)-9a-(2,3-dimethoxystyryl)-7-ethyl-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556023 ZINC04000153 Natural Product (3aS)-3a-[(E)-2-(4-butoxy-3-methoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00555985 ZINC02160281 Natural Product (E)-7-ethyl-9a-(2-methoxystyryl)-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555999 ZINC02134723 Natural Product (3aS)-3a-[(E)-2-(4-ethoxy-3-methoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00556015 ZINC04000204 Natural Product (E)-9a-(2,5-dimethoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555991 ZINC02125827 Natural Product (E)-9a-(2,5-dimethoxystyryl)-7-ethyl-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556022 ZINC04000192 Natural Product (E)-9a-(4-ethoxy-3-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556006 ZINC02120199 Natural Product (3aR)-3a-[(E)-2-(2,3-dimethoxyphenyl)ethenyl]-6-ethyl-4,4-dimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00555984 ZINC02125829 Natural Product AC1LWOJT
CFAMM00555998 ZINC08788790 Natural Product AC1O78QD
CFAMM00556014 ZINC04000203 Natural Product (E)-9a-(4-isopropoxy-3-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555990 ZINC02115777 Natural Product (E)-7-ethyl-9a-(3-methoxystyryl)-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556005 ZINC02161039 Natural Product (E)-9a-(4-(benzyloxy)-3-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556020 ZINC02136917 Natural Product (3aR)-3a-[(E)-2-(2,3-dimethoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00555997 ZINC02127158 Natural Product AC1LWQK8
CFAMM00556013 ZINC08918617 Natural Product (E)-9a-(3-methoxy-4-((4-methylbenzyl)oxy)styryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555989 ZINC02126028 Natural Product (3aR)-6-ethyl-3a-[(E)-2-(4-methoxyphenyl)ethenyl]-4,4-dimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00556004 ZINC02138904 Natural Product AC1LX5D1
CFAMM00556019 ZINC04000179 Natural Product (E)-9a-(3-methoxy-4-((2-methylallyl)oxy)styryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555996 ZINC02130307 Natural Product (E)-9a-(4-butoxy-3-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556011 ZINC02130068 Natural Product AC1LWUBQ
CFAMM00555988 ZINC04000121 Natural Product (E)-9a-(3-methoxy-4-propoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556003 ZINC00536509 Natural Product (3aR)-3a-[(E)-2-(4-methoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00556018 ZINC04000112 Natural Product (E)-9a-(4-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00555995 ZINC02136768 Natural Product (3aR)-3a-[(E)-2-(2,5-dimethoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00556010 ZINC04000196 Natural Product (E)-9a-(3-methoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556026 ZINC02131884 Natural Product (3aR)-3a-[(E)-2-[3-methoxy-4-(2-methylprop-2-enoxy)phenyl]ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00556002 ZINC00540811 Natural Product (3aR)-3a-[(E)-2-(3-methoxyphenyl)ethenyl]-4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one
CFAMM00555987 ZINC02160284 Natural Product AC1LXTWD
CFAMM00556017 ZINC02128474 Natural Product AC1LWS0G
CFAMM00555994 ZINC08791991 Natural Product (E)-9a-(3-ethoxy-4-(pentyloxy)styryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556008 ZINC08918631 Natural Product (E)-9a-(4-(benzyloxy)-3-ethoxystyryl)-7,9,9-trimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one
CFAMM00556025 ZINC01062498 Natural Product (S,E)-9a-(3,4-dimethoxystyryl)-9,9-dimethyl-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26186 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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