CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFNP970
Family Name Putative NP ZINC02127056 Family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00556206 Functional Category Natural Product
Superfamily Nuclear receptor ROR-gamma and Beta-lactamase ligand CHEMBL1304903 Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Histamine H3 receptor Ligand A-349821 Family 49 228
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Histone deacetylase 1 Inhibitor N-hydroxy-8-(2-methoxyphenyl)-... 2 14
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Mu-type opioid receptor ligand 3-[(3R,4R)-1-[(2,4-dimethoxyphe... 2 4
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 11
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Histamine H1 receptor ligand SureCN7952197 family 1 0
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Putative NP ZINC02099241 Family 12 0
Putative NP ZINC00892468 Family 2 0
Putative NP ZINC00519603 Family 8 1
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0
3-(3,4-dimethoxyphenyl)-3-[3-(7-methoxy-4,8-dimethyl-2-oxochro... 4 0
4-methyl-7-[(4-methylpiperazin-1-ium-1-yl)methyl]-3-oxo-1-benz... 14 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00556209 ZINC02127055 Natural Product 2-methoxy-4-(4-oxo-3,4-dihydro-2H-benzo[e][1,3]oxazin-2-yl)phenyl isobutyrate
CFAMM00556208 ZINC02127056 Natural Product [2-methoxy-4-[(2R)-4-oxo-2,3-dihydro-1,3-benzoxazin-2-yl]phenyl] 2-methylpropanoate
CFAMM00556207 ZINC00206896 Natural Product (2R)-2-(4-methoxyphenyl)-2,3-dihydro-1,3-benzoxazin-4-one
CFAMM00556206 ZINC00206894 Natural Product 2-(4-methoxyphenyl)-2H-benzo[e][1,3]oxazin-4(3H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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