CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 1,3-dimethylcyclohepta[c]furan-8-one NP 8-hydroxy-6-(4-methoxyphenyl)-1,3-dimethyl-4h-cyclohepta[c]furan-4-one Family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00556254 Functional Category Natural Product
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5-diphenyl-furan-3-yl)-phenyl-methanone Superfamily
Class Class 1672

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
DNA Binder Methoxsalen Family 10 1638
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5... 1 9
Kappa-type opioid receptor Ligand Salvinorin B Butoxymethyl Et... 38 215
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 78
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0


External ID

Functional Category

Molecule Name

CFAMM00556248 ZINC12890505 Natural Product 8-methoxy-6-(4-(2-(4-methoxyphenyl)-2-oxoethoxy)phenyl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556254 ZINC00111977 Natural Product 6-(4-ethoxyphenyl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556247 ZINC06624093 Natural Product 8-methoxy-1,3-dimethyl-6-(4-(2-(5-methylfuran-2-yl)-2-oxoethoxy)phenyl)-4H-cyclohepta[c]furan-4-one
CFAMM00556253 ZINC00111980 Natural Product 6-(4-hydroxyphenyl)-8-methoxy-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556246 ZINC01321758 Natural Product (E)-8-ethoxy-6-(2-methoxystyryl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556252 ZINC00111972 Natural Product 8-methoxy-6-(4-methoxyphenyl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556245 ZINC00519667 Natural Product 8-hydroxy-6-(4-methoxyphenyl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one
CFAMM00556251 ZINC02144736 Natural Product 8-ethoxy-1,3-dimethyl-6-(4-propoxyphenyl)-4H-cyclohepta[c]furan-4-one
CFAMM00556250 ZINC02145231 Natural Product 8-hydroxy-1,3-dimethyl-6-(4-propoxyphenyl)-4H-cyclohepta[c]furan-4-one
CFAMM00556249 ZINC00525785 Natural Product (E)-8-methoxy-6-(2-methoxystyryl)-1,3-dimethyl-4H-cyclohepta[c]furan-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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