CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 11
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 11

Member Superfamilies of This Class

Superfamily NameFamilies
Arachidonate 5-lipoxygenase Inhibitor Ici 207968 Superfamily 4
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 4
Caspase-1 and Lethal factor Binder Superfamily 3
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrino... 9
D(4) dopamine receptor Ligand ABT-670 Superfamily 4
Enoyl-[acyl-carrier-protein] reductase [NADH] inhibitor pyridi... 5
Huntingtin and Retinal dehydrogenase 1 Binder Superfamily 1
NADPH oxidase 4 inhibitor SureCN2216820 Superfamily 5
Putative Imidazonaphthyridines In Patent US6194425,US6699878,U... 2
Putative Pyridyl Alkylene Amidinoureas In Patent US4387225,US4... 2
SUR2-type K(ATP) channel Ligand Nicorandil Superfamily 6

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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