CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 137
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 11

Member Superfamilies of This Class

Superfamily NameFamilies
Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... 5
Beta-secretase 1 and Growth hormone secretagogue receptor type... 3
Cannabinoid receptor 1 and Cytochrome P450 3A4 Binder Superfamily 4
Caspase-1 and Cytochrome P450 3A4 Binder Superfamily 7
Caspase-3 and Caspase-1 Inhibitor Pralnacasan Superfamily 3
HIV protease Inhibitor Saquinavir Superfamily 9
HIV-1 protease Inhibitor Atazanavir Superfamily 10
Interstitial collagenase and Cellular tumor antigen p53 Binder... 2
Neuromedin-K receptor Ligand SB222200 Superfamily 7
Pol polyprotein Binder Superfamily 12 3
Protein farnesyltransferase subunit beta and Protein farnesylt... 5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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