CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 142
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5
Estrogen receptor and Estrogen receptor beta Binder Superfamil... 11
Histamine H1 receptor Ligand Doxepin Superfamily 9
Histamine H3 receptor Binder Superfamily 7 4
Inositol monophosphatase 1 and 5-hydroxytryptamine receptor 1A... 3
Menin and Cytochrome P450 2D6 Binder Superfamily 5
Oestrogen receptor Ligand Lasofoxifene Superfamily 4
Putative NP ZINC01322649 Superfamily 8
Sodium-dependent noradrenaline transporter and Cytochrome P450... 2
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4
Voltage-gated sodium channel Ligand SB-221420-A Superfamily 4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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