CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 144
Functional Category Approved Drug with Natural Product
No. of Members 18

Member Superfamilies of This Class

Superfamily NameFamilies
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 7
Aurora kinase B and Aurora kinase A Inhibitor PF-03814735 Supe... 6
Beta-secretase 1 and Cathepsin D Binder Superfamily 3 7
Beta-secretase 1 and Serine/threonine-protein kinase B-raf Bin... 4
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(tria... 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Super... 6
Cell division cycle 7-related protein kinase and Glycogen synt... 17
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 10
Cyclin-dependent kinase 4 Inhibitor PD-332991 Superfamily 8
Glucokinase and Cannabinoid receptor 2 Binder Superfamily 4
Histone deacetylase 6 Inhibitor ACY-1215 Superfamily 14
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 11
Mast/stem cell growth factor receptor Kit and Vascular endothe... 17
Metabotropic glutamate receptor 2 and Translocator protein Bin... 7
P2X purinoceptor 7 and Protein farnesyltransferase subunit bet... 4
Putative Bicyclic Nitrogen Heterocycles and Bicyclic Nitrogen ... 2
Reverse transcriptase/RNaseH and ALK tyrosine kinase receptor ... 6
Ribosomal protein S6 kinase alpha-3 and Mitogen-activated prot... 4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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