CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 147
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 14

Member Superfamilies of This Class

Superfamily NameFamilies
Amg 423 Superfamily 7
Carbonic anhydrase 2 and Carbonic anhydrase 4 Binder Superfami... 2
Cathepsin D and Beta-secretase 1 Binder Superfamily 13 3
Cathepsin K and Cathepsin S Binder Superfamily 7 5
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4
Histone deacetylase 6 Inhibitor N-(quinolin-3-yl)-6-(sulfamoyl... 9
Huntingtin and Menin Binder Superfamily 2 1
Melanocortin receptor 3 and Melanocortin receptor 4 Binder Sup... 7
Neuropeptide Y receptor type 5 and Prelamin-A/C Binder Superfa... 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13
Putative 2-substituted Ergolines and Optionally 11- To 13-subs... 2
RAC-gamma serine/threonine-protein kinase Inhibitor MK-2206 Su... 1
Reverse transcriptase Inhibitor Delavirdine Superfamily 2
Smoothened homolog Binder Superfamily 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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