CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 216
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 22

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 1A and Prelamin-A/C Binder Superf... 9
Beta-lactamase and Cruzipain Binder Superfamily 17 2
Beta-lactamase and Thyrotropin receptor Binder Superfamily 4 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 Binde... 3
Caspase-3 and Acetylcholinesterase Binder Superfamily 5
Chymase inhibitor 4-[(2R,3S)-1-(benzhydrylcarbamoyl)-3-[(2-eth... 3
Cruzipain and Beta-lactamase Binder Superfamily 8 6
Cytochrome P450 2D6 and Delta-type opioid receptor Binder Supe... 6
D(2) dopamine receptor Ligand Sulpiride Superfamily 3
D(3) dopamine receptor and Prelamin-A/C Binder Superfamily 4
Disintegrin and Thrombopoietin Binder Superfamily 5
DNA polymerase beta and Ferritin light chain Binder Superfamily 4
DNA-dependent protein kinase catalytic subunit and Phosphatidy... 4
Histone deacetylase Inhibitor Abexinostat Superfamily 5
Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 21 5
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 5
Muscleblind-like protein 1 and Retinal dehydrogenase 1 inhibit... 3
Nuclear receptor ROR-gamma and Beta-lactamase ligand CHEMBL130... 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7
Proto-oncogene tyrosine-protein kinase Src Binder Superfamily 2
Putative Patent EP1054882,WO9941248 Superfamily 3
Sodium- and chloride-dependent glycine transporter 1 Binder Su... 3

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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