CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 24
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
Acetylcholinesterase and Butyrylcholinesterase Binder Superfam... 4
Alpha-1A adrenergic receptor Ligand RS-17053 Superfamily 8
Beta adrenergic receptor ligand monosubstituted indole derivat... 7
Beta-lactamase and 3C-like protease Binder Superfamily 4
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 5
DNA Binder Primaquine Superfamily 3
Epidermal growth factor receptor and Receptor tyrosine-protein... 4
Melatonin receptor type 1A Ligand Melatonin Superfamily 6
Metabotropic glutamate receptor 5 and Platelet-derived growth ... 5
Na+-K+-ATPase transmembrane protein Inhibitor Sanguinarine Sup... 3
Small conductance calcium-activated potassium channel protein ... 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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