CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 280
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 11

Member Superfamilies of This Class

Superfamily NameFamilies
Alpha adrenergic receptor Ligand Phenoxybenzamine Superfamily 8
Cholinesterase and Acetylcholinesterase Binder Superfamily 16 2
Cytochrome P450 2D6 and Sodium channel protein type 1 subunit ... 4
D(3) dopamine receptor and D(1A) dopamine receptor Binder Supe... 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 10
Histamine H3 receptor Ligand A-331440 Superfamily 5
Nuclear receptor ROR-gamma and Lysosomal alpha-glucosidase Bin... 2
Putative Inotropic Agents In Patent US4670445,US4578387,EP0154... 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2
Transporter and Alpha-2C adrenergic receptor Binder Superfamily 5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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