CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 281
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 18

Member Superfamilies of This Class

Superfamily NameFamilies
Amyloid beta A4 protein and Amine oxidase [flavin-containing] ... 6
Beta-1 adrenergic receptor Ligand Acebutolol Superfamily 7
Beta-lactamase and Ferritin light chain Binder Superfamily 36 2
Beta-lactamase and Inositol monophosphatase 1 Binder Superfami... 4
Caspase-3 and Beta-lactamase Binder Superfamily 6
Dihydroorotate dehydrogenase (quinone), mitochondrial and Beta... 3
Follicle-stimulating hormone receptor Binder Superfamily 5
Histone deacetylase 2 and Metabotropic glutamate receptor 5 Bi... 10
Lethal(3)malignant brain tumor-like protein 1 and Beta-lactama... 7
Menin and Cruzipain Binder Superfamily 7 2
Microtubule-associated protein tau and Cytochrome P450 2D6 Bin... 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 7
Pol polyprotein and Glucagon receptor Binder Superfamily 15
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1536110 Superf... 4
Putative 3-methylidenyl-2-indolinone Modulators Of Protein Kin... 5
Putative Anthelmintically Active Benzenepropanamide Derivative... 2
Putative Thermosensitive Recording Material With A High Fog Re... 7
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 8

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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